Combination of Mixed Drugs vs Ibuprofen: a Randomized Clinical Trial

NCT ID: NCT07133360

Last Updated: 2025-08-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-02-01

Study Completion Date

2025-05-01

Brief Summary

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Combination of vitamins and melatonine compared with the conventional use of ibuprofen after surgical third molar extraction

Detailed Description

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Conditions

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Swelling Lips &Amp; Face Pain Trismus

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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Ibuprofen 400

Three ibuprofen 400 doses

Group Type ACTIVE_COMPARATOR

Third molar extraction

Intervention Type PROCEDURE

Surgical third molar extraction with conventional medication

Coctail mixed Drugs

Vitamin D, Vitamin B and Melatonine at night instead Ibuprofen

Group Type EXPERIMENTAL

Third molar extraction

Intervention Type PROCEDURE

Surgical third molar extraction with conventional medication

Interventions

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Third molar extraction

Surgical third molar extraction with conventional medication

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Healthy volunteers, non ibuprofen allergic, presence of impacted lower third molar

Exclusion Criteria

* Diseases that avoid surgical intervention
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Universidad Complutense de Madrid

OTHER

Sponsor Role lead

Responsible Party

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Jesús Torres García Denche

Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Complutense University of Madrid

Madrid, , Spain

Site Status

Countries

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Spain

Other Identifiers

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2019-000736-27

Identifier Type: -

Identifier Source: org_study_id

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