Meloxicam Versus Ibuprofen for Pain Control After Third Molar Exodontia in Adult Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

PHASE4

Total Enrollment

68 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-12-15

Study Completion Date

2025-01-20

Brief Summary

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Third molar extraction is a common dental procedure, offently related with pain and swelling. The purpose of this study is to evaluate if Meloxicam has a better effect relieving pain after the extraction than Ibuprofen, one of the most common pain relieving drugs administered after this procedure.

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Detailed Description

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Summary: Third molar extractions are one of the most common procedures in dental practice. However, pain and swelling as postoperative sequelae are inevitable. Depending on the level of pain, which can range from moderate to severe, this symptomatology can be accompanied with pharmacological treatment, thus generating a less traumatic recovery for the patient. It is currently known that non-steroidal anti-inflammatory drugs (NSAIDs) have proven to be effective for the treatment of mild and moderate postoperative pain. Due to the wide variety of NSAIDs, it is important to know how to choose the most effective option when indicating one therapeutic option over another.

Objective: To evaluate the postoperative analgesic effectiveness of meloxicam (7.5 mg) compared to ibuprofen (400 mg) in patients undergoing third molar(s) extraction.

Design: Randomized controlled clinical trial, double-masked, designed according to CONSORT guideline requirements.

Conditions

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Dental Pain Sensation Disorders

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Group A control. Ibuprofen

Ibuprofen 400mg tablets, 1 every 8 hours for 3 days will be administered for post-surgical pain.

Group Type ACTIVE_COMPARATOR

meloxicam 7,5mg

Intervention Type DRUG

Comparison of analgesic efficacy of Meloxicam Vs Ibuprofen

Group B experimental. Meloxicam

Meloxicam 7.5mg tablets, 1 every 12 hours for 3 days will be administered for post-surgical pain.

Group Type ACTIVE_COMPARATOR

meloxicam 7,5mg

Intervention Type DRUG

Comparison of analgesic efficacy of Meloxicam Vs Ibuprofen

Interventions

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meloxicam 7,5mg

Comparison of analgesic efficacy of Meloxicam Vs Ibuprofen

Intervention Type DRUG

Other Intervention Names

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ibuprofen 400mg

Eligibility Criteria

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Inclusion Criteria

Maxillary or mandibular third molar with semi or fully erupted crown.

Exclusion Criteria

Patients with Systemic pathologies. Presence of third molar localized infection. Completely included third molar crown. Periodontal compromise. Pregnant or breastfeeding women. Patients with hypersensitivity to NSAIDs. Patients with a history of drug abuse. Patients who had taken any drug in the previous 24 hours. Intervention (exodontia) time longer than 45 minutes.

Minimum Eligible Age

18 Years

Maximum Eligible Age

59 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes