Analgesic Effects of Cannabidiol for Simple Tooth Extractions in Dental Patients
NCT ID: NCT04271917
Last Updated: 2022-05-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE3
68 participants
INTERVENTIONAL
2020-02-24
2022-03-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Treatment As Usual (TAU)
Participants will receive a 5-day supply of acetaminophen 500mg and ibuprofen 200mg.
Instructions for use: Take one tablet of each medication at the same time every 4-6 hours as needed for pain.
acetaminophen 500mg and ibuprofen 200mg combo
standard of care
Placebo
Participants will receive a 5-day supply (15mL) of inactive placebo in a dropper vial.
Instructions for use: Place 0.5mL of oil under tongue for 30 seconds then swallow. Use every 4-6 hours as needed for pain.
placebo
Inactive placebo oil to imitate CBD oil
CBD 17mg/mL
Participants will receive a 5-day supply (15mL) of cannabidiol 17mg/mL.
Instructions for use: Place 0.5mL of oil under tongue for 30 seconds then swallow. Use every 4-6 hours as needed for pain.
cannabidiol
Use of cannabidiol as an alternative to standard of care treatment of acute pain.
CBD 37 mg/mL
Participants will receive a 5-day supply (15mL) of cannabidiol 37mg/mL.
Instructions for use: Place 0.5mL of oil under tongue for 30 seconds then swallow. Use every 4-6 hours as needed for pain.
cannabidiol
Use of cannabidiol as an alternative to standard of care treatment of acute pain.
Interventions
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cannabidiol
Use of cannabidiol as an alternative to standard of care treatment of acute pain.
placebo
Inactive placebo oil to imitate CBD oil
acetaminophen 500mg and ibuprofen 200mg combo
standard of care
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Operation must be a simple tooth extraction which does not result in an opioid prescription
* 18 years of age or older
* Have regular and direct access to a device that can send and receive texts and willing to accept any associated charges for 24 text messages
Exclusion Criteria
* Contraindication to acetaminophen
* Contraindication to cannabidiol or hemp oil
* Contraindication to peppermint oil
* Contraindication to almond or other tree nuts
* Currently taking a form of cannabidiol and unwilling to stop use for one week post surgery
18 Years
ALL
No
Sponsors
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University of Tennessee
OTHER
Responsible Party
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Karen Derefinko, PhD
Assistant Professor
Principal Investigators
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Karen J Derefinko, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Tennessee
Ammaar H Abidi, DDS, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Tennessee
Locations
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University of Tennessee Health Science Center
Memphis, Tennessee, United States
Countries
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Other Identifiers
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20-07123-XP
Identifier Type: -
Identifier Source: org_study_id
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