Cerebromicrovascular Effects of Time-Restricted Eating in Older Adults

NCT ID: NCT05488652

Last Updated: 2024-01-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-11-17

Study Completion Date

2024-01-10

Brief Summary

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The central hypothesis of this study is that closer adherence to time restricted eating (TRE) will improve endothelial function, neurovascular (NVC) responses, resulting in improved cognitive performance, potentially through activation of SIRT1-dependent vasoprotective pathways.

Detailed Description

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This hypothesis will be tested by assessing the effect of TRE (not more than 10hr eating window each day for 6 months) in healthy adults (≥21 years of age). The group of subjects enrolled into TRE arm will be compared to control group. All participants will be randomized into either arm of the study.

Conditions

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Time Restricted Eating

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Control

no intervention

Group Type NO_INTERVENTION

No interventions assigned to this group

Time restricted eating

not more than 10 hrs. eating window daily goal for 6 months

Group Type EXPERIMENTAL

Time restricted eating

Intervention Type OTHER

not more than 10 hrs. eating window daily goal for 6 months

Interventions

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Time restricted eating

not more than 10 hrs. eating window daily goal for 6 months

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

-Healthy adults ≥21 years of age

Exclusion Criteria

-Inability to read or write in English
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Oklahoma

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Stefano Tarantini, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Oklahoma

Locations

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University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, United States

Site Status

Countries

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United States

Other Identifiers

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14856

Identifier Type: -

Identifier Source: org_study_id

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