Neurocognitive Effects of Meal Timing in a One-Meal-a-Day Regimen

NCT ID: NCT07181057

Last Updated: 2025-09-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-03-01

Study Completion Date

2025-05-15

Brief Summary

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Objectives: The purpose of this study is to examine how meal timing in a one-meal-a-day (OMAD) regimen influences neurocognitive outcomes.

Methods: Twelve cognitively active participants (academics, students, software engineers) will complete three randomized OMAD conditions, consuming a standardized isocaloric meal at 08:00, 12:30, or 18:00. ERPs will be recorded during a computerized Stroop task to evaluate peak amplitudes and latencies under congruent and incongruent conditions. Resting-state EEG will be measured under eyes-open and eyes-closed conditions. Behavioral performance on the Stroop task, including reaction time and accuracy, will also be assessed.

Detailed Description

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Conditions

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Fasting State Cognitive Abilities

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Single Group (Crossover)

Arm Title: Morning Meal (08:00) Arm Type: Experimental Intervention: Other: One-meal-a-day (OMAD) Arm Description: Participants consume a single standardized isocaloric meal at 08:00. Neurocognitive outcomes (ERP, resting-state EEG, Stroop performance) are assessed during morning (before meal) and afternoon (approximately 6 hours post-meal) sessions.

Arm Title: Midday Meal (12:30) Arm Type: Experimental Intervention: Other: One-meal-a-day (OMAD) Arm Description: Participants consume a single standardized isocaloric meal at 12:30. Neurocognitive outcomes (ERP, resting-state EEG, Stroop performance) are assessed during morning (before meal) and afternoon (approximately 6 hours post-meal) sessions.

Arm Title: Evening Meal (18:00) Arm Type: Experimental Intervention: Other: One-meal-a-day (OMAD) Arm Description: Participants consume a single standardized isocaloric meal at 18:00. Neurocognitive outcomes (ERP, resting-state EEG, Stroop performance) are assessed during morning (before mea

Group Type EXPERIMENTAL

one-meal-a-day (OMAD)

Intervention Type OTHER

Arm Title: Morning Meal (08:00)

Intervention: Other: One-meal-a-day (OMAD)

Description: Participants consume a single isocaloric meal at 08:00.

Arm Title: Midday Meal (12:30)

Intervention: Other: One-meal-a-day (OMAD)

Description: Participants consume a single isocaloric meal at 12:30.

Arm Title: Evening Meal (18:00)

Intervention: Other: One-meal-a-day (OMAD)

Description: Participants consume a single isocaloric meal at 18:00.

Interventions

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one-meal-a-day (OMAD)

Arm Title: Morning Meal (08:00)

Intervention: Other: One-meal-a-day (OMAD)

Description: Participants consume a single isocaloric meal at 08:00.

Arm Title: Midday Meal (12:30)

Intervention: Other: One-meal-a-day (OMAD)

Description: Participants consume a single isocaloric meal at 12:30.

Arm Title: Evening Meal (18:00)

Intervention: Other: One-meal-a-day (OMAD)

Description: Participants consume a single isocaloric meal at 18:00.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Male, 20 to 45 years of age

Right-handed

Normal or corrected-to-normal vision

Cognitively active individuals (academic staff, graduate students, or software/algorithm engineers)

Regular sleep-wake schedule during the week preceding the experiment

Ability to abstain from caffeine, alcohol, or psychoactive substances for at least 24 hours prior to each test session

Body mass index between 18.5 and 30 kg/m²

Exclusion Criteria

History of neurological, psychiatric, metabolic, or sleep disorders

Current use of medications that affect the central nervous system

Shift work or irregular sleep patterns (verified by sleep diary)

Prior experience with one-meal-a-day dietary routines

Body mass index below 18.5 or above 30 kg/m²
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Erzurum Technical University

OTHER

Sponsor Role lead

Responsible Party

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Süleyman Ulupınar

Associate Professor of Exercise Physiology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Erzurum Technical University Sport Sciences Faculty

Erzurum, Erzurum, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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ETU-OMAD-2025-01

Identifier Type: -

Identifier Source: org_study_id

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