Identifying Drug-related Problems at ED Triage (DRP-EDiT) V1

NCT ID: NCT05476705

Last Updated: 2023-02-01

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 110 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2023-04-30
• Study Completion Date: 2023-09-30

Brief Summary

Up to a third of patients who visit emergency departments (EDs) do so because they have an issue with medicines prescribed by their doctor or purchased over the counter. For example, some patients might experience side effects (e.g., sickness), whereas others may feel their prescribed medicine is not working and want an alternative. While some patients who visit EDs know they have a problem with their medication, some are not aware. Furthermore, drug-related problems (DRPs) may not be identified by ED triage systems which are used to sort patients' priority for treatment. The currently used system in the UK (Manchester Triage System) mentions drugs infrequently and does not support the identification of the most common DRPs. For this project, DRPs include medication errors, adverse drug events, and adverse drug reactions. This project aims to revise the triage system to support the discovery of patients' medication problems when they are triaged by a nurse upon arrival to the ED.

After identification, problems with a patient's medication should be dealt with by the healthcare professional who is most appropriate to manage that particular issue. For example, a patient who has been prescribed a new medicine but already takes 20 medicines will likely benefit from a review by a pharmacist in the ED. This project will aim to support the management of patients who might benefit from care provided by pharmacists by providing them with this care.

As well as ensuring medication problems are identified at triage, and that pharmacists are involved in helping to deal with those problems, this project will also try to understand how we can investigate how pharmacists actually make a difference to the care of ED patients.

A multi-step approach (Stages A-F) is proposed to answer the question "How can patient DRPs be identified, triaged and managed in the ED?" In summary, the steps include: STAGE A, a systematic review and scoping survey; STAGE B, researcher visits to ED sites to shadow ED staff; STAGE C, Interviews with healthcare professionals (including those shadowed in STAGE B) to validate findings of site visits and explore topics in more depth; STAGE D, developing additional drug-related content for the Manchester Triage System; STAGE E, involving a panel of experts in a RAND appropriateness method to rate the content developed in STAGE D; STAGE F, testing the revised triage system for a future pilot study involving interviews with staff visited in STAGE B.

Conditions

Medication Administered in Error; Medication Adverse Effects; Medication Reaction

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: CROSS_SECTIONAL

Eligibility Criteria

Inclusion Criteria

• STAGE A: ED clinicians at UK-wide NHS trusts
• STAGE B: ED staff from 8 NHS sites across the UK
• STAGE C: ED staff from 8 NHS sites across the UK
• STAGE E: Clinicians and academics with expertise in Emergency Care and/or ED Triage
• STAGE F: ED staff from 8 NHS sites across the UK

Exclusion Criteria

• Those who do not consent or who are unable to consent

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Pharmacy Research UK

UNKNOWN

Sponsor Role: collaborator

University of Manchester

OTHER

Sponsor Role: collaborator

Ashford and St. Peter's Hospitals NHS Trust

OTHER

Sponsor Role: collaborator

Anglia Ruskin University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Daniel Greenwood

Role: PRINCIPAL_INVESTIGATOR

Anglia Ruskin University

Central Contacts

Daniel Greenwood

Role: CONTACT

daniel.greenwood@aru.ac.uk

01245683082

Other Identifiers

IRAS 307523

Identifier Type: -

Identifier Source: org_study_id