Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
72 participants
INTERVENTIONAL
2022-05-01
2023-11-23
Brief Summary
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Increasing activity levels in middle age appears to improve muscle function and bone health. However, there is a lack of evidence in how muscle function responds to low impact resistance exercise in middle aged females.
This study aims to assess the effectiveness and the mechanisms associated with building muscle as well as the effect on quality of life in middle aged (40-60 years) females using a low impact resistance training programme.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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Intervention group
Supervised exercise program week 1-12, unsupervised exercise week 13-24.
Supervised resistance exercise program
12 week supervised low impact resistance training program
Unsupervised resistance exercise program
12 week unsupervised low impact resistance training program
Control group
Maintain habitual activity week 1-12, unsupervised exercise week 13-24.
Unsupervised resistance exercise program
12 week unsupervised low impact resistance training program
Interventions
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Supervised resistance exercise program
12 week supervised low impact resistance training program
Unsupervised resistance exercise program
12 week unsupervised low impact resistance training program
Eligibility Criteria
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Inclusion Criteria
* Body mass index \<30kg/m2 and \>18.5kg/m2
* Considered moderately active according to the 7 day International Physical Activity Questionnaire (IPAQ) (Craig et al., 2003)
* Self-reported as healthy (absence of injury or disease).
* Availability and willingness to attended 12 weeks of exercises classes 4-5 times per week at St Luke's Campus Exeter and participate in the study lasting a total of 26 weeks.
Exclusion Criteria
* Current diagnosis of a chronic disease such as diabetes, autoimmune disease, cardiovascular disease, kidney disease.
* Hysterectomy and/or ovariectomy.
* Currently prescribed hormone replacement therapy.
* Hypertension (BP ≥149/90 mm/Hg)
* Either current smoker, or history of smoking in the past 6 months.
* Currently taking supplements that have been shown to impact muscle function and muscle mass, such as creatine, in the last 6 months.
* Prescribed medications that have been shown to impact muscle function and muscle mass, such as steroids, in the last 6 months.
* History of epilepsy.
* Current or recent injury within the last 6 months that may affect their ability to carry out the resistance training program.
* Advised not to exercise by their General Practitioner or medical professional.
* Resistance training consistently for 3 or more times per week for the last 2 months
40 Years
60 Years
FEMALE
Yes
Sponsors
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P.volve LLC
UNKNOWN
University of Exeter
OTHER
Responsible Party
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Principal Investigators
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Francis Stephens
Role: PRINCIPAL_INVESTIGATOR
University of Exeter
Locations
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University of Exeter
Exeter, , United Kingdom
Countries
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References
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Svensen E, Koscien CP, Alamdari N, Wall BT, Stephens FB. A Novel Low-Impact Resistance Exercise Program Increases Strength and Balance in Females Irrespective of Menopause Status. Med Sci Sports Exerc. 2025 Mar 1;57(3):501-513. doi: 10.1249/MSS.0000000000003586. Epub 2024 Nov 6.
Other Identifiers
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309199
Identifier Type: OTHER
Identifier Source: secondary_id
2021-22-13
Identifier Type: -
Identifier Source: org_study_id
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