Osseodensification and Dental Implant Stability

NCT ID: NCT05376020

Last Updated: 2022-05-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

46 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-05-13

Study Completion Date

2024-05-13

Brief Summary

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Osseointegration refers to the formation of a structural and functional bone-to-implant interface, without the interposition of soft tissue. Successful osseointegration will provide long term success for the dental implant. Primary implant stability, is the mechanical stability between bone and the implant at the time of insertion and is key to initiate a successful osseointegration.

Both primary implant stability and osseointegration are affected by the density of the bone where the implant is placed. A relatively new technique known as osseodensification (OD) has been developed and uses specially designed burs (Densah burs). Compared to conventional drills (CD) that remove bone (subtractive drilling) these burs are designed so that they can rotate in a counterclockwise (CCW) (non subtractive) direction which allows bone to be preserved and compacted into the wall of the osteotomy site. These drills therefore theoretically maintain bone volume which then creates higher bone density and bone to implant contact allowing better implant primary stability.

This study will be a randomised control trial comparing OD to CD with regards to implant stability and bone levels. Considering the increased cost of OD, available literature must support a significant clinical benefit of OD over CD to consider them for clinical use. This study will aim to reinforce available clinical research and address some of the limitations of the current evidence to aid clinicians in making an evidenced-based decision on the use of OD when poor bone density could compromise implant success.

Detailed Description

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Conditions

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Osseointegration Osseodensification

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Densah Burs

Intervention Group

Group Type EXPERIMENTAL

Densah Burs

Intervention Type DEVICE

Densah Burs will be used in the intervention group

Conventional Burs

Control Group

Group Type ACTIVE_COMPARATOR

Conventional Burs

Intervention Type DEVICE

Conventional Burs will be used in the control group

Interventions

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Densah Burs

Densah Burs will be used in the intervention group

Intervention Type DEVICE

Conventional Burs

Conventional Burs will be used in the control group

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

Patient Level

* Male or Female, 18 years old or over
* Capacity to provide informed consent
* Willing to comply with study appointment schedule Willing to maintain a diary of symptoms
* Planned for provision of dental implant(s) at Dublin Dental University Hospital

Site Level

* Location: maxilla
* Sufficient bone volume for implant placement without the need for bone graft/augmentation; alveolar ridge of minimum 6mm width for standard implants (implant diameter 4mm) and of minimum 7mm for wider implants (implant diameter 5mm)

Exclusion Criteria

Patient Level

* Plaque score \>20%
* Bleeding score \>20%
* Tobacco smoking
* Uncontrolled systemic disease
* Use of systemic medications with an expected impact on bone healing (e.g. bisphosphonates)
* Pregnancy or lactation
* Lack of capacity to give an informed consent

Site Level

* Location: mandible
* Insufficient bone volume for implant placement, requiring bone graft/augmentation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Dublin, Trinity College

OTHER

Sponsor Role lead

Responsible Party

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Ioanna Politi

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Dublin Dental Hospital/Trinity College Dublin

Dublin, , Ireland

Site Status RECRUITING

Countries

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Ireland

Central Contacts

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Ioanna Politi, B.Dent.Sc

Role: CONTACT

+3530862773128

Ioannis Polyzois, DMD

Role: CONTACT

Facility Contacts

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Ioanna Politi

Role: primary

References

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Politi I, Honari B, Winning L, Polyzois I. The Effect of Osseodensification on Implant Stability and Marginal Bone Levels: A Randomized Control Clinical Trial. Clin Exp Dent Res. 2025 Feb;11(1):e70126. doi: 10.1002/cre2.70126.

Reference Type DERIVED
PMID: 40205940 (View on PubMed)

Other Identifiers

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IPoliti

Identifier Type: -

Identifier Source: org_study_id

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