Pain-relieving Methods After Laparoscopic Hemicolectomy

NCT ID: NCT05273281

Last Updated: 2022-11-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

255 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-06-01

Study Completion Date

2025-02-01

Brief Summary

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Effects of Transabdominal Plain Block and Quadratus Lumborum Block After Laparoscopic Hemicolectomy. The pain relief, bowel function and discharge.

Detailed Description

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This study is proposed to explore the effects of transabdominal plane block and quadratus lumborum block after laparoscopic hemicolectomy.

After laparoscopic hemicolectomy there is a need for good analgesia. When the analgesia is adequate the patients mobilisation, bowel function and discharge is faster. Earlier, epidural block has been used for the analgesia but now the hemicolectomy is laparoscopic procedure and there is no need for central block anymore. Still patients needs opioids after the operation. Because of the opioids side effects, there is a need to find better analgesia methods.

In this study investigators compare peripheral nerve blocks, transabdominal plane and quadratus lumborum, for analgesia after laparoscopic hemicolectomy. Also investigators are comparing these analgesia methods and traditional orally analgesics. Patients receive transabdominal or quadratus lumborum block after induction using ropivacaine 5 mg/ml 20 ml per side. The third group is a control group witch analgesia is taken care with traditional orally analgesics.

After surgery investigators follow postoperative pain, opiate consumption, bowel function, nausea and mobilisation.

Investigators coal is to find if the transabdominal plain block or quadratus lumborum block prefer traditional analgesia methods after laparoscopic hemicolectomy.

Conditions

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Postoperative Pain Nerve Block

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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TAQLA

Transabdominal plain block -group. Ropivacaine Hydrochloride Inj 5mg/ml 20 ml perineurally per side.

Group Type EXPERIMENTAL

Transabdominal plane block

Intervention Type PROCEDURE

Peripheral nerve block

TAQLB

Quadratus lumborum block -group. Ropivacaine Hydrochloride Inj 5mg/ml 20 ml perineurally per side.

Group Type EXPERIMENTAL

Quadratus lumborum block

Intervention Type PROCEDURE

Peripheral nerve block

TAQLC

Control group. Pain relief only with intravenous and peroral drugs.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Transabdominal plane block

Peripheral nerve block

Intervention Type PROCEDURE

Quadratus lumborum block

Peripheral nerve block

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

Adult elective hemicolectomy patients

Exclusion Criteria

Age under 18 years Complicated diabetes mellitus Lack of finnish language skill and/or co-operation Chronic pain Use of drugs that significantly influences the metabolism of paracetamol or opiate Steroid medication in regular use Significant liver-, lung- or kidney disfunction
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Tampere University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jenni Kanerva, Phd

Role: PRINCIPAL_INVESTIGATOR

Tampere University Hospital

Maija-Liisa Kalliomäki, PhD

Role: STUDY_DIRECTOR

Tampere University Hospital

Locations

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Tampere University Hospital

Tampere, , Finland

Site Status RECRUITING

Countries

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Finland

Central Contacts

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Maija-Liisa Kalliomäki, PhD

Role: CONTACT

+358 3 311 69424

Jenni Kanerva, PhD

Role: CONTACT

+358 3 311 67415

Facility Contacts

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Maija-Liisa Kalliomäki, PhD

Role: primary

+358 3 311 69424

Jenni Kanerva, PhD

Role: backup

+358 3 311 67415

Other Identifiers

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R21075M

Identifier Type: -

Identifier Source: org_study_id

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