Analgesic Effect of Quadratus Lumborum Block in Laparoscopic Hemicolectomy
NCT ID: NCT04848363
Last Updated: 2021-06-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
60 participants
INTERVENTIONAL
2021-06-16
2022-05-30
Brief Summary
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Detailed Description
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All patients will receive post operative multimodal analgesia using paracetamol, ketoprofen, tramadol, and trimeperidine if numerical rating scale \> 3 The study assumes use of QL block by levobupivacaine.in comparison with placebo in order to demonstrate the effectiveness of QL block during the operation.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
* Control group: patients receiving general anesthesia with propofol, fentanyl and cisatracurium for induction and sevoflurane, fentanyl and cisatracurium for maintaining anesthesia. Patients receiving postoperative multimodal intravenous analgesia with paracetamol, ketoprofen, tramadol, and trimeperidine. Before surgery will be performde bilateral blockade of the QL muscle with normal saline.
* Study group: patients receiving general anesthesia with propofol, fentanyl and cisatracurium for induction and sevoflurane, fentanyl and cisatracurium for maintaining anesthesia. Patients receiving postoperative multimodal intravenous analgesia with paracetamol, ketoprofen, tramadol, and trimeperidine. The QL blockade will be performed under ultrasound guidance using 20 ml of a solution of levobupivacaine 2.5 mg / ml.
TREATMENT
TRIPLE
Study Groups
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Study group
patients receiving general anesthesia with propofol, fentanyl and cisatracurium for induction and sevoflurane, fentanyl and cisatracurium for maintaining anesthesia. Patients receiving postoperative multimodal intravenous analgesia with paracetamol, ketoprofen, tramadol, and trimeperidine. In this group, after induction of anesthesia before the operation, bilateral blockade of the square dorsi muscle is performed under ultrasound guidance using 20 ml of a solution of levobupivacaine 2.5 mg / ml.
Quadratus lumborum block
QL block will be used for perioperative anesthesia. The blockade will be performed bilaterally by levobupivacaine (20ml) at concentration 0.25%.
Control group
patients receiving general anesthesia with propofol, fentanyl and cisatracurium for induction and sevoflurane, fentanyl and cisatracurium for maintaining anesthesia. Patients receiving postoperative multimodal intravenous analgesia with paracetamol, ketoprofen, tramadol, and trimeperidine. In this group, after induction of anesthesia before surgery, bilateral blockade of the square dorsi muscle is performed under ultrasound guidance using 20 ml of saline.
Quadratus lumborum block
QL block will be used for perioperative anesthesia. The blockade will be performed bilaterally by levobupivacaine (20ml) at concentration 0.25%.
Interventions
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Quadratus lumborum block
QL block will be used for perioperative anesthesia. The blockade will be performed bilaterally by levobupivacaine (20ml) at concentration 0.25%.
Eligibility Criteria
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Inclusion Criteria
* Patient's willingness and ability to sign an informed consent document
Exclusion Criteria
* Chronic pain syndrome and associated opioid use.
* Coagulopathy
* Uncontrolled diabetes mellitus
* Physical Status Classification System scale above 3
* Diseases associated with the pathology of the hypothalamus
* Diseases associated with the pathology of the pituitary gland
* Diseases associated with the pathology of the adrenal glands
18 Years
ALL
No
Sponsors
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Petrovsky National Research Centre of Surgery
OTHER
Responsible Party
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Evgenii Bespalov,MD
Doctor of the department of anesthesiology and resuscitation
Locations
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Petrovsky Research National Centre of Surgery ( Petrovsky NRCS)
Moscow, , Russia
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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BEK25011994
Identifier Type: -
Identifier Source: org_study_id
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