Transmuscular Quadratus Lumborum Block for Postoperative Pain After Laparoscopic Adrenalectomy

NCT ID: NCT03942237

Last Updated: 2020-01-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

72 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-05-10

Study Completion Date

2019-09-02

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This prospective, randomized control study aims to compare the analgesic effect, satisfaction with anesthesia and analgesia between single-injection QLB (quadratus lumborum block)+general anesthesia (GA) and general anesthesia (GA) alone in patients undergoing laparoscopic adrenalectomy.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pain Management Nerve Block Laparoscopic Adrenalectomy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

single-injection QLB (quadratus lumborum block)

Single-injection of QLB with local anesthetic is given preoperatively

Group Type EXPERIMENTAL

single-injection QLB(quadratus lumborum block)

Intervention Type PROCEDURE

Inject 0.4ml/kg 0.5% ropivacaine between quadratus lumborum and psoas major muscle

Device: The curved (C1-5) probe of Ultrasound Scanner Philips CX50 is used for scan

Drug: single dose ropivacaine 0.4ml/kg 0.5% ropivacaine is given immediately after the correct position of needle tip is verified.

Placebo control

Single-injection of QLB with NS is given preoperatively

Group Type PLACEBO_COMPARATOR

Placebo Control

Intervention Type PROCEDURE

Inject 0.4ml/kg saline between quadratus lumborum and psoas major muscle

Device: The curved (C1-5) probe of Ultrasound Scanner Philips CX50 is used for scan

Drug: single dose 0.4ml/kg 0.9% NS is given immediately after the correct position of the needle tip is verified

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

single-injection QLB(quadratus lumborum block)

Inject 0.4ml/kg 0.5% ropivacaine between quadratus lumborum and psoas major muscle

Device: The curved (C1-5) probe of Ultrasound Scanner Philips CX50 is used for scan

Drug: single dose ropivacaine 0.4ml/kg 0.5% ropivacaine is given immediately after the correct position of needle tip is verified.

Intervention Type PROCEDURE

Placebo Control

Inject 0.4ml/kg saline between quadratus lumborum and psoas major muscle

Device: The curved (C1-5) probe of Ultrasound Scanner Philips CX50 is used for scan

Drug: single dose 0.4ml/kg 0.9% NS is given immediately after the correct position of the needle tip is verified

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age 18-70 yrs
* American Society of Anesthesiologists physical statusⅠ-Ⅲ
* Undergo laparoscopic adrenalectomy
* Informed consent

Exclusion Criteria

* a known allergy to the medications being used for anesthesia
* coagulopathy or on anticoagulants
* chronic opioid therapy or history of substance abuse
* participating in another RCT
* inability to properly describe postoperative pain to investigators (e.g., language barrier, neuropsychiatric disorder).
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Peking Union Medical College Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Cui Xulei

Attending physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Yuguang Huang

Role: STUDY_CHAIR

PUMCH

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Peking Union Medical College Hospital

Beijing, , China

Site Status

Countries

Review the countries where the study has at least one active or historical site.

China

References

Explore related publications, articles, or registry entries linked to this study.

Yuan Q, Lu S, Cui X, Zhang Y, Xie Y, Zhang Y, Yan W, Ji Z, Huang Y. Transmuscular quadratus lumborum block for postoperative pain and recovery after laparoscopic adrenalectomy: a randomized controlled trial. BMC Anesthesiol. 2021 Nov 9;21(1):274. doi: 10.1186/s12871-021-01494-4.

Reference Type DERIVED
PMID: 34753425 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

cuixulei8

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.