Quadratus Lumborum Block : Effect on Acute Pain and Quality of Recovery After Laparoscopic Renal Surgery

NCT ID: NCT02841982

Last Updated: 2019-05-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-08-31

Study Completion Date

2018-12-31

Brief Summary

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This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay and incidence of chronic pain,et al. between single-injection QLB(quadratus lumborum block)+ intravenous patient-controlled analgesia (IPCA) and intravenous patient-controlled analgesia (IPCA) alone in patients undergoing laparoscopic renal surgeries.

Detailed Description

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Conditions

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Laparoscopic Renal Surgery Pain Management Nerve Block

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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single-injection QLB(quadratus lumborum block)

Single-injection of QLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)

Group Type EXPERIMENTAL

single-injection QLB(quadratus lumborum block)

Intervention Type PROCEDURE

Inject local anesthetics in between quadratus lumborum and psoas major without continuous local infusion

Philip CX50 Ultrasound Scanner

Intervention Type DEVICE

The curved (C1-5) probe of Philip CX 50 Ultrasound Scanner is used for scan

PAJUNK StimuLong

Intervention Type DEVICE

single dose ropivacaine

Intervention Type DRUG

* 0.6ml/kg 0.5% ropivacaine with 1:200,000 adrenaline.
* given immediately after the correct position of the tip of the needle has been verified.

Morphine given as IPCA(intravenous patient controlled analgesia)

Intervention Type DRUG

bolus: 1.5\~2mg, lock time: 10min, 1h limitation: 6\~8mg

IPCA

postoperative IPCA is given alone

Group Type ACTIVE_COMPARATOR

Morphine given as IPCA(intravenous patient controlled analgesia)

Intervention Type DRUG

bolus: 1.5\~2mg, lock time: 10min, 1h limitation: 6\~8mg

Interventions

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single-injection QLB(quadratus lumborum block)

Inject local anesthetics in between quadratus lumborum and psoas major without continuous local infusion

Intervention Type PROCEDURE

Philip CX50 Ultrasound Scanner

The curved (C1-5) probe of Philip CX 50 Ultrasound Scanner is used for scan

Intervention Type DEVICE

PAJUNK StimuLong

Intervention Type DEVICE

single dose ropivacaine

* 0.6ml/kg 0.5% ropivacaine with 1:200,000 adrenaline.
* given immediately after the correct position of the tip of the needle has been verified.

Intervention Type DRUG

Morphine given as IPCA(intravenous patient controlled analgesia)

bolus: 1.5\~2mg, lock time: 10min, 1h limitation: 6\~8mg

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Age 18-70 yrs
* American Society of Anesthesiologists physical statusⅠ-Ⅲ
* Undergo laparoscopic nephrectomy
* Informed consent

Exclusion Criteria

* A known allergy to the drugs being used
* Coagulopathy, on anticoagulants
* Analgesics intake, history of substance abuse
* Participating in the investigation of another experimental agent
* Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)
Minimum Eligible Age

17 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cui Xulei

OTHER

Sponsor Role lead

Responsible Party

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Cui Xulei

Attending physician

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Yuguang Huang, MD.

Role: STUDY_CHAIR

Peking Union Medical College Hospital

Locations

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Xulei CUI

Beijing, Beijing Municipality, China

Site Status

Countries

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China

Other Identifiers

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cuixulei3

Identifier Type: -

Identifier Source: org_study_id

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