Quadratus Lumborum Block Versus Erector Spinae Block in Laparoscopic Cholecystectomy

NCT ID: NCT04689633

Last Updated: 2021-03-04

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 60 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2019-04-15
• Study Completion Date: 2020-01-15

Brief Summary

The patients were randomly allocated into 3 parallel groups of 20 patients in each group by using computer generated tables. group(Q):received bilateral sonar-guided quadratus lumborum bolck using 20 ml bupivacaine 0.25%on each side.group(E): received bilateral ultrasound-guided erector spinae block using 20 ml bupivaciane 0.25%on each side. group(C):didn't received any block

Detailed Description

on arrival to the operative room all patients were monitored with standared monitoring. then IV cannula were inserted. preoxygenation with 100% oxygen and induction of GA by 1mic/kg fentanyl and 2 mg/kg of 1%propofol. endotracheal intubation was facilitated by 0.5mg/kg of atracurium. isoflurane 1-2% with oxygen was used for anesthetic maintenance and 0.15 mg/kg intermittent doses of atracurium to maintain adequate muscle relaxation. ventilation was controlled to maintain end tidal CO2 at 35-40 mmHg and SaO2 between 95-100. after stabilization of the patient's hemodynamics and before surgical incision, quadratus lumborum and erector Spinae block were performed according to patient's group by the same anesthetist with the patient in lateral or prone position respectively.

Conditions

Postoperative Analgesia

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

Quadratus lumborum block

received bilateral ultrasound-guided Quadratus lumborum block using 20 ml bupivacaine 0.25% on each side

Group Type: ACTIVE_COMPARATOR

nerve block

Intervention Type: PROCEDURE

bilateral ultrasound-guided posterior quadratus lumborum block was done in the lateral decubitus and linear or curvilinear probe was used according to the depth and placed in the midaxillary line in the transverse plane above the iliac crest

Erector spinae block

received bilateral ultrasound-guided erector spinae block using 20 ml bupivacaine 0.25% on each side

Group Type: ACTIVE_COMPARATOR

nerve block

Intervention Type: PROCEDURE

bilateral ultrasound-guided posterior quadratus lumborum block was done in the lateral decubitus and linear or curvilinear probe was used according to the depth and placed in the midaxillary line in the transverse plane above the iliac crest

Control

didn't received any block

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

nerve block

bilateral ultrasound-guided posterior quadratus lumborum block was done in the lateral decubitus and linear or curvilinear probe was used according to the depth and placed in the midaxillary line in the transverse plane above the iliac crest

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• American society of anesthesiologists(ASA) physical status1and2 scheduled for elective cholecystectomy under general anesthesia

Exclusion Criteria

• Allergy to studed drugs
• morbid obesity
• patient refusal
• infection at the side of the bolck
• emergency laparoscopic cholecystectomy
• if laparoscopic procedure converted to open

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 70 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Minia University

OTHER

Sponsor Role: lead

Responsible Party

Shadwa Rabea Mohamed

Lecturer

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Abeer Hassaneen, MD

Role: STUDY_CHAIR

Assistant professor

Locations

Faculty of Medicine

Minya, , Egypt

Countries

Egypt

Other Identifiers

135-12/2018

Identifier Type: -

Identifier Source: org_study_id