Supra-inguinal Fascia Iliaca Compartment Block on Postoperative Management in Total Hip Arthroplasty by Posterior Approach

NCT ID: NCT04574479

Last Updated: 2022-05-17

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: PHASE4
• Total Enrollment: 86 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2020-12-16
• Study Completion Date: 2021-09-02

Brief Summary

Find the impact of supra-inguinal fascia iliaca compartment block on postoperative pain management after total hip arthroplasty by posterior surgical approach

Detailed Description

ASA physical status 1, 2 and 3 patients scheduled to undergo elective surgery of total hip arthroplasty under spinal anesthesia.

The investigators would like to study the impact of supra-inguinal fascia iliaca block on postoperative pain management after total hip arthroplasty by posterior surgical approach. The principal investigator perform this block with ultrasound technique. The investigators also want to observe if this loco-regional new approach to fascia iliaca block could have influence on opioid side effects, postoperative nausea and vomiting, length of hospitalisation and first mobilisation side effects.

Conditions

Arthropathy of Hip

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: SUPPORTIVE_CARE
• Blinding Strategy: DOUBLE

Study Groups

Placebo

Placebo group: patients have multimodal analgesia without fascia-iliaca compartment block

Group Type: PLACEBO_COMPARATOR

Multimodal analgesia and PCA morphine pump

Intervention Type: DRUG

Patients in placebo group have classical multimodal approach to postoperative analgesia with morphine administration by PCA pump

Fascia iliaca block

Patients in this arm have multimodal analgesia with supra-inguinal fascia iliaca compartment block before surgery

Group Type: EXPERIMENTAL

Supra-inguinal fascia iliaca compartment block

Intervention Type: PROCEDURE

Ultrasound guided loco-regional technique as described by Desmet et al. Fascia iliaca compartment block with in-plane 40 ml ropivacaine 0,375% injection between the ilio-psoas muscle and the internal oblique muscle.

Patients in SFICB group have classical multimodal approach to postoperative analgesia with morphine administration by PCA pump

Multimodal analgesia and PCA morphine pump

Intervention Type: DRUG

Patients in placebo group have classical multimodal approach to postoperative analgesia with morphine administration by PCA pump

Interventions

Supra-inguinal fascia iliaca compartment block

Ultrasound guided loco-regional technique as described by Desmet et al. Fascia iliaca compartment block with in-plane 40 ml ropivacaine 0,375% injection between the ilio-psoas muscle and the internal oblique muscle.

Patients in SFICB group have classical multimodal approach to postoperative analgesia with morphine administration by PCA pump

Intervention Type: PROCEDURE

Multimodal analgesia and PCA morphine pump

Patients in placebo group have classical multimodal approach to postoperative analgesia with morphine administration by PCA pump

Intervention Type: DRUG

Eligibility Criteria

Inclusion Criteria

• Adults patients scheduled to undergo elective surgery of total hip arthroplasty by posterior surgical aboard

Exclusion Criteria

• Patient refusal
• Allergy to used medications or local infection.
• Pregnancy
• Obesity with body mass index > 35
• History of chronic pain or fibromyalgia
• Drug (opioids) addiction
• Treatment with corticosteroids for more than 6 months
• Severe kidney or liver diseases
• Mental disorders or serious neurological diseases

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 85 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Liege

OTHER

Sponsor Role: lead

Responsible Party

Jean François Brichant

Head of Anesthesiology Department

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

CHU de Liège

Liège, , Belgium

Countries

Belgium

References

Desmet M, Balocco AL, Van Belleghem V. Fascia iliaca compartment blocks: Different techniques and review of the literature. Best Pract Res Clin Anaesthesiol. 2019 Mar;33(1):57-66. doi: 10.1016/j.bpa.2019.03.004. Epub 2019 Apr 17.

Reference Type: BACKGROUND

PMID: 31272654 (View on PubMed)

Carella M, Beck F, Piette N, Denys S, Kurth W, Lecoq JP, Bonhomme VL. Effect of suprainguinal fascia iliaca compartment block on postoperative opioid consumption and functional recovery in posterolateral-approached total hip arthroplasty: a single-blind randomized controlled trial. Reg Anesth Pain Med. 2022 Jun 15:rapm-2021-103427. doi: 10.1136/rapm-2021-103427. Online ahead of print.

Reference Type: DERIVED

PMID: 35705263 (View on PubMed)

Other Identifiers

2020/67

Identifier Type: -

Identifier Source: org_study_id