Immunity and Nasal Fungal Colonization

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

58 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-08-20

Study Completion Date

2020-07-27

Brief Summary

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Fungal colonization causes opportunistic infection that may manifest when the host's immune status deteriorates. The purpose of this study was to determine the prevalence of fungal colonization in immunocompromised subjects compared to healthy controls.

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Detailed Description

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Conditions

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Colonization, Asymptomatic

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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healthy volunteers

No interventions assigned to this group

immunocompromised subjects

nasal irrigation

Intervention Type OTHER

regular saline nasal rinse

Interventions

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nasal irrigation

regular saline nasal rinse

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Immunocompromised subjects included those who had known risk factors for fungal infection, including malignant diseases, diabetes, autoimmune disorders, renal or hepatic insufficiency, organ transplantation, or use of immunosuppressants
* Healthy volunteers had neither sinonasal symptoms nor nasal endoscopic inflammation.