Funguria in Hospitalized Patients

NCT ID: NCT00138502

Last Updated: 2019-02-04

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 926 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2001-09-17
• Study Completion Date: 2008-12-08

Brief Summary

The purpose of the study is to test the hypothesis that a subpopulation of patients with candiduria are at significant risk for disseminated disease and would benefit from treatment, while others are at low risk from complications and therefore require no antifungal therapy.

Detailed Description

This protocol will attempt to generate a detailed clinical profile of patients with funguria and identify subgroups of patients with funguria at high risk for candiduria and determine the relative risks for obtaining candiduria. In addition, it will look at identifying subgroups of patients with funguria at high risk for candidemia and identifying subgroups of patients with funguria at high risk for death. Finally, it will attempt to determine if funguria independently predicts fungemia or death. Data will be complemented by surveillance of a comparable population without funguria.

Conditions

Candidiasis

Study Design

• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

1. Subjects with fungi isolated from the urine of any colony count.

2. Patients seen at either Harbor-UCLA Medical Center or Cedars Sinai Medical Center.

Exclusion Criteria

1. Persons with a previously positive urine fungal culture during the current hospital admission.

• Maximum Eligible Age: 99 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

Sponsor Role: lead

Locations

Cedars Sinai Medical Center

Los Angeles, California, United States

UCLA Center For Vaccine Research

Torrance, California, United States

Countries

United States

Other Identifiers

02-050

Identifier Type: -

Identifier Source: org_study_id