Diagnostic Performance of an Aspergillus-specific Nested PCR Assay in Cerebrospinal Fluid Samples

NCT ID: NCT01614145

Last Updated: 2020-04-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-09-30

Study Completion Date

2020-12-31

Brief Summary

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Multicentre, diagnostic study evaluating the performance of an aspergillus-specific PCR in cerebrospinal fluid samples of immunocompromised patients for identification of central nervous system aspergillosis.

Detailed Description

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Conditions

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Focus: Immunocompromised Individuals at High Risk of Aqcuiring Invasive Aspergillosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Proven/probable CNS IA

Immunocompromised patients with proven/probable invasive CNS Aspergillosis based on modified criteria by the EORTC/MSG

No interventions assigned to this group

Possible/No CNS IA

Immunocompromised patients with possible/NoIA invasive CNS Aspergillosis based on modified criteria by the EORTC/MSG

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Host factors
* Informed consent

Exclusion Criteria

* none
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Heidelberg University

OTHER

Sponsor Role lead

Responsible Party

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Dieter Buchheidt

Prof. Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Dieter Buchheidt, MD

Role: PRINCIPAL_INVESTIGATOR

Germany: Mannheim University Hospital, University of Heidelberg

Locations

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Freiburg University Hospital

Freiburg im Breisgau, Baden-Würrtemberg, Germany

Site Status

Mannheim University Hospital

Mannheim, Baden-Würrtemberg, Germany

Site Status

Frankfurt (Oder) General Hospital

Frankfurt (Oder), Brandenburg, Germany

Site Status

Countries

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Germany

Other Identifiers

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CSF Aspergillus PCR

Identifier Type: -

Identifier Source: org_study_id

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