Efficacy and Safety of Amphotericin B and Azoles in the Treatment of Invasive Fungal Disease

NCT ID: NCT06819410

Last Updated: 2025-02-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-05-01

Study Completion Date

2025-02-01

Brief Summary

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Efficacy and safety of amphotericin B and azoles in the treatment of invasive fungal disease

Detailed Description

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The medical records, demographic characteristics and clinical data of patients with invasive fungal disease treated with amphotericin B or azoles were collected through the electronic medical record system of Sichuan Provincial People's Hospital from 2021 to 2024. To evaluate the efficacy and safety of these two types of drugs.

Conditions

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Invasive Fungal Disease

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Treatment with polyene antifungal drugs

The dosage and course of Amphotericin B or Amphotericin B cholesteryl sulphate complex were determined by clinicians, and this study was registered according to clinical practice

No interventions assigned to this group

Treatment with azole antifungal drugs

The dosage and course of triazoles or imidazole antifungal drugs were determined by clinicians, and this study was registered according to clinical practice

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* There is no age limit, gender is not limited
* Patients with invasive fungal disease who are treated with polyene antifungals or azole antifungals should be treated for ≥ 7 days.

Exclusion Criteria

* Patients with incomplete data or other factors affecting the clinical outcome judgement
* Patients who are judged by the investigator to be unsuitable to participate in this study.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sichuan Provincial People's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Lingai Pan

Deputy Chief Physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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lingai PP Pan, PhD

Role: STUDY_CHAIR

Sichuan Provincial People's Hospital

Locations

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Sichuan Provincial People's Hospital

Chengdu, Sichuan, China

Site Status RECRUITING

Countries

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China

Central Contacts

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lingai Pan, PhD

Role: CONTACT

17708130236

Facility Contacts

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lingai Pan, PhD

Role: primary

17708130236

Other Identifiers

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Lunshen(Research)No.818,2024

Identifier Type: -

Identifier Source: org_study_id

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