The Effects of Sevoflurane and Desflurane on QT Interval Measured With Cardiac Electrophysiological Balance Index

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-02-28

Study Completion Date

2022-07-31

Brief Summary

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The primary aim of this study is to compare the effects of sevoflurane and desflurane on the QT interval. The secondary aim of this study is to compare the effects of drugs used in the induction and maintenance of anesthesia on the QT interval by calculating the Bazzet formula and iCEB.

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Detailed Description

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Conditions

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Sevoflurane Desflurane QT Interval Electrophysiological Balance Index

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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sevoflurane

General Anesthesia procedure with sevoflurane

Group Type ACTIVE_COMPARATOR

12- derivation Electrocardiography

Intervention Type DIAGNOSTIC_TEST

6 precordial and 4 extremity electrodes will be placed at appropriate anatomical points and a total of 6 12-lead ECGs will be taken at different anesthesia depths before anesthesia induction and throughout the operation.

desflurane

General Anesthesia procedure with desflurane

Group Type ACTIVE_COMPARATOR

12- derivation Electrocardiography

Intervention Type DIAGNOSTIC_TEST

6 precordial and 4 extremity electrodes will be placed at appropriate anatomical points and a total of 6 12-lead ECGs will be taken at different anesthesia depths before anesthesia induction and throughout the operation.

Interventions

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12- derivation Electrocardiography

6 precordial and 4 extremity electrodes will be placed at appropriate anatomical points and a total of 6 12-lead ECGs will be taken at different anesthesia depths before anesthesia induction and throughout the operation.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

1. ASA I-II-III risk group
2. the operation time is longer than 1 hour in the Urology department.

Exclusion Criteria

1. bundle branch block in preoperative ECG,
2. Non-sinus heart rhythm,
3. QT length in preoperative ECG,
4. using drugs that cause known QT prolongation ( beta-blocker drugs using will be included),
5. development of malignant arrhythmia that will disrupt hemodynamics in the intraoperative period,
6. patients with electrolyte disorders,
7. patient refusal -

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No