Epidemiology of Gunshot Wounds Injuries Admitted in ICU in France

NCT ID: NCT05224570

Last Updated: 2025-12-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-01-01

Study Completion Date

2022-06-17

Brief Summary

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In civilian practice, the incidence of firearm violence depends on the country. In high income countries, most cases are reported in the USA or South Africa. In these countries, gunshot wounds (GSW) represent 20% of death cases in trauma centers, more than motor vehicle collisions.

The mortality in civilian practice occurs during the first 24 hours following GSW, mainly due to hemorrhage and traumatic brain injury, though long term effects on physical and psychological outcomes have also been shown.

Some factors of mortality specific to GSW have been established: multiples wounds, homicide vs suicide attempt, impact zone, or firearm caliber.

Few specific guidelines have been published concerning civilian GSW management. These cases are mostly treated in standard guidelines, such as hemorrhagic shock or traumatic brain injury guidelines. As in other trauma mechanisms, the "platinum ten minutes and golden hour" concept is applicable.

In Europe, the incidence of civilian GSW is much lower and few European studies have been published recently. Penetrating injuries in Europe are less likely to be GSW, and are more often self-inflicted than in the USA. In addition, European studies are heterogeneous, due to the difference in populations, healthcare systems and GSW being grouped with stabbing wounds under the label "penetrating trauma".

However, there is a global concern in Europe regarding a potential rise of GSW, with higher severity score than conventional trauma patients and often necessitate ICU admission. Studies analyzing data from different European countries show significantly different ICU admission rates for overall GSW, ranging from 17% up to 30%.

Therefore, the investigators conducted a multicenter, retrospective study on four French University Hospitals aiming to describe the epidemiology (mortality and type of organ damage) and identify prognosis factors of civilian GSW admitted in ICU.

Detailed Description

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Conditions

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Gunshot Wound

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Gunshot wounds admitted in ICU

patient with Gunshot wounds admitted to ICU

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Admission for gunshot wound care in ICU between 1st of January 2015 and June 30th 2021 at Nimes University Hospital, Marseille North University Hospital, Montpellier University Hospital, Toulon Military Teaching Hospital.
* Patient ≥ 15 years old

Exclusion Criteria

* Patient \< 15 years old
* Patient who objected to the use of their data.
Minimum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Nīmes

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Loic ROUGERIE

Role: PRINCIPAL_INVESTIGATOR

CHU NIMES

Laurent MULLER, Md, PhD

Role: STUDY_DIRECTOR

CHU NIMES

Locations

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CHU de NIMES

Nîmes, , France

Site Status

Countries

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France

References

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Rougerie L, Charbit J, Mezzarobba M, Leone M, Duclos G, Meaudre E, Cungi PJ, Bartoli C, Thierry GR, Roger C, Muller L. Epidemiology of civilian's gunshot wound injuries admitted to intensive care unit: A retrospective, multi-center study. Injury. 2024 Oct;55(10):111735. doi: 10.1016/j.injury.2024.111735. Epub 2024 Jul 25.

Reference Type RESULT
PMID: 39153311 (View on PubMed)

Other Identifiers

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LOCAL/2021/LR-01

Identifier Type: -

Identifier Source: org_study_id

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