Comparison of Two Different Approach TAP Block on Pain Management of Laparoscopic Nephrectomy

NCT ID: NCT05188794

Last Updated: 2024-04-05

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 88 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-01-01
• Study Completion Date: 2022-05-15

Brief Summary

Primary aim is to compare the effectiveness of the posterior approach Transversus abdominis plane block (P-TAP) and the lateral approach Transversus abdominis plane block (L-TAP) technique on the pain management of the laparoscopic nephrectomy in terms of visual analog pain scale and postoperative opioid consumption. Secondary aim is to compare complication rates of the two techniques.

Detailed Description

Patients included in the study will be randomized into two groups (group L and group P) in the preoperative period. Following routine anesthesia induction TAP block will be applied to group L patients with the lateral approach technique, and to group P patients with the posterior approach technique. Regional block complications will be recorded.

Standard laparoscopic nephrectomy surgical method will be applied. 1g of paracetamol and 4mg of dansetron will be administered to both groups 15 minutes before the end of the operation. The pain intensity of the patients will be questioned and VAS values will be recorded at 0, 1, 2, 6, 12 and 24 hours postoperatively.

Conditions

Analgesia, Patient-Controlled; Postoperative Pain, Acute

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: SUPPORTIVE_CARE
• Blinding Strategy: QUADRUPLE

Study Groups

group L

Lateral transversus abdominis plane(TAP) block

Group Type: ACTIVE_COMPARATOR

lateral tap block

Intervention Type: PROCEDURE

In the axial plane on the midaxillary line between the subcostal margin and the iliac crest with a linear probe using a 12 cm insulated nerve block needle is advanced in planely from skin, external, and internal oblique muscles to the target of fascial plane between the internal oblique and the transversus abdominis muscles.

Group P

Posterior transversus abdominis plane block

Group Type: ACTIVE_COMPARATOR

posterior tap block

Intervention Type: PROCEDURE

In the axial plane on the midaxillary line a linear probe using a 12 cm insulated nerve block needle is advanced posteriorly to the most posterior limit of the TAP between the internal oblique and transversus abdominis muscles.

Interventions

lateral tap block

In the axial plane on the midaxillary line between the subcostal margin and the iliac crest with a linear probe using a 12 cm insulated nerve block needle is advanced in planely from skin, external, and internal oblique muscles to the target of fascial plane between the internal oblique and the transversus abdominis muscles.

Intervention Type: PROCEDURE

posterior tap block

In the axial plane on the midaxillary line a linear probe using a 12 cm insulated nerve block needle is advanced posteriorly to the most posterior limit of the TAP between the internal oblique and transversus abdominis muscles.

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• ASAI-III patients undergoing laparoscopic nephrectomy
• 18<BMI<40

Exclusion Criteria

• infection at the block site
• coagulation disorder
• pregnancy
• kidney failure
• liver failure
• heart failure
• allergy to local anesthetics
• patient refusal

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 75 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Ankara City Hospital Bilkent

OTHER

Sponsor Role: lead

Responsible Party

Serap Diker

Anaestesia and Reanimation Specialist

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

MİYASE SERAP DİKER, DOCTOR

Role: PRINCIPAL_INVESTIGATOR

ANKARA CİTY HOSPİTAL

Locations

Ankara City Hospital,Bilkent

Ankara, Cankay, Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

E1-21-1814

Identifier Type: -

Identifier Source: org_study_id