Aging and Marijuana: Benefits, Effects, and Risks

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

326 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-09-20

Study Completion Date

2025-05-25

Brief Summary

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Investigators will gather data on both the beneficial and harmful effects of edible cannabis of varying composition (THC-only vs. CBD-only vs. THC+CBD), and will examine the process by which older adult cannabis users decide what type of cannabis product is preferred.

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Detailed Description

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Older adults are currently the fastest growing group of cannabis users in the U.S, and are more likely to use cannabis for medicinal purposes (e.g., pain, trouble sleeping, depression/anxiety) than for recreational purposes, despite having little data to guide their decisions about what type of product to use. This project utilizes a patient-centered observational design to recruit and assess older adults who are interested in using cannabis compared to a control group who is not interested in cannabis use. Investigators will gather data on both the beneficial and harmful effects of edible cannabis of varying composition (THC-only vs. CBD-only vs. THC+CBD), and will examine the process by which older adult cannabis users decide what type of cannabis product is preferred.

Conditions

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Cannabis Use

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Cannabis Users

Older adults (60 and up) who report pain, sleep problems, and/or negative mood (anxiety and/or depression) and who desire to use cannabis for these issues (n=300)

Choice of cannabis product

Intervention Type BEHAVIORAL

Participants choose and purchase their own cannabis product

Cannabis Non-users

Older adults (60 and up) who report pain, sleep problems, and/or negative mood (anxiety and/or depression) and do NOT desire to use cannabis for these issues (n=50)

No interventions assigned to this group

Interventions

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Choice of cannabis product

Participants choose and purchase their own cannabis product

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* At least 60 years of age
* Able to provide informed consent
* Cannabis Users: Must not currently use cannabis more than 7 times per month and not for pain, sleep, depression or anxiety in the past 6 months
* Cannabis Non-users: Should NOT have used cannabis in the past year and have not used regularly (e.g., more than weekly) for more than one year in the past 20 years
* Cannabis Users: Must be interested in using cannabis for at least one of the following complains: pain, sleep problems, depression, anxiety
* Non-users: Must NOT be interested in using cannabis but have at least one of the following complaints: pain, sleep problems, depression, anxiety
* Cannabis users: must be comfortable using edible cannabis and having a mobile laboratory (Dodge van) parked at their home
* Female participants must be postmenopausal
* Comfortable reading and writing in English
* Planning to stay in the Boulder/Denver area for the next month
* Must be comfortable with blood draws

Exclusion Criteria

* Blood alcohol level \> 0 at screening (to sign consent form)
* Report of other drug use (cocaine, opiates, methamphetamine) in the past 90 days or fail urine screen for any of these drugs
* Past or current diagnosis of psychosis
* Current use of antipsychotic medications
* Heavy drinking; Alcohol Use Disorder Identification Test (AUDIT) test score \>8
* Inability/discomfort/unwillingness with getting in and out of the mobile laboratory van
* History of vertigo or falls within the past six months

Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes