Bimanual Robotic Exoskeletal Platform for the Treatment of the Upper Limb in Patients With Stroke. A Feasibility Study

NCT ID: NCT05176600

Last Updated: 2022-04-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-01-10

Study Completion Date

2022-09-30

Brief Summary

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The purpose of the study is to test the technical functionality, safety, and feasibility of a bimanual robotic exoskeletal platform and associated serious games in order to offer information on technological and functional advances that will be included in the device's finalization.

In addition, a secondary goal will be to assess the therapeutic effects of a rehabilitation therapy based on the bimanual configuration, comparing it to a unimanual treatment delivered on the same platform (using the specific configuration).

Detailed Description

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Conditions

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Stroke

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Bimanual group

In this group, patients will perform a robotic rehabilitation based on bimanual serious games

Group Type EXPERIMENTAL

Robotic rehabilitation using the Arm Light Exoskeleton Rehab Station (ALEx RS) and bimanual serious games

Intervention Type DEVICE

Patients will undergo a bimanual 30-session robotic rehabilitation, using the robot ALEx RS with the bimanual configuration and the related serious games. Each session will last 45 minute. Daily sessions will be provided, five days a week.

Unimanual group

In this group, patients will perform a robotic rehabilitation based on unimanual serious games

Group Type ACTIVE_COMPARATOR

Robotic rehabilitation using the Arm Light Exoskeleton Rehab Station (ALEx RS) and unimanual serious games

Intervention Type DEVICE

Patients will undergo a unimanual 30-session robotic rehabilitation, using the robot ALEx RS with the unimanual configuration and the related serious games.Daily sessions will be provided, five days a week.

Interventions

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Robotic rehabilitation using the Arm Light Exoskeleton Rehab Station (ALEx RS) and bimanual serious games

Patients will undergo a bimanual 30-session robotic rehabilitation, using the robot ALEx RS with the bimanual configuration and the related serious games. Each session will last 45 minute. Daily sessions will be provided, five days a week.

Intervention Type DEVICE

Robotic rehabilitation using the Arm Light Exoskeleton Rehab Station (ALEx RS) and unimanual serious games

Patients will undergo a unimanual 30-session robotic rehabilitation, using the robot ALEx RS with the unimanual configuration and the related serious games.Daily sessions will be provided, five days a week.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* height between 150 and 190 cm;
* weight not exceeding 130 kg;
* ischemic injury;
* first cortical and supra-tentorial event;
* moderate motor deficit of the upper limb (score on the Fugl-Meyer Assessment - Upper Extremity between 29 and 42);
* time since stroke event between 1 and 6 months;
* trunk control test score greater than or equal to 48;
* healthy bone density and skeleton that does not suffer from unhealed fractures.

Exclusion Criteria

* Relevant medical comorbidities (severe neurological diseases, cardiovascular diseases, diabetes / unstabilized hypertension);
* Cognitive impairment that prevents understanding of the exercises administered;
* Unavailability to provide informed consent;
* Pregnant women;
* Severe spasticity (Ashworth 4);
* Major muscle contractures;
* Excessive asymmetry in the length of the arms;
* Upper limb prostheses;
* Excessive joint limitations that make it difficult or painful to use the device;
* Use of pacemakers or implantation of active devices;
* Patients who already participate in another clinical study or who are already undergoing another similar robotic rehabilitation treatment.
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fondazione Don Carlo Gnocchi Onlus

OTHER

Sponsor Role collaborator

Wearable Robotics srl.

INDUSTRY

Sponsor Role lead

Responsible Party

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Lucia Lencioni

CEO

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Irene Aprile, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Fondazione Don Carlo Gnocchi Onlus

Locations

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Fondazione Don Carlo Gnocchi

Rome, , Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Irene Aprile, MD, PhD

Role: CONTACT

+390633086553

Facility Contacts

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Irene Aprile, MD, PhD

Role: primary

+390688036553

Other Identifiers

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FDG_Birehab_2021

Identifier Type: -

Identifier Source: org_study_id

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