Efficacy Study of FES Controlled by Electromyographic Signal for the Treatment of Upper Limb in Post-stroke Patients

NCT ID: NCT03019744

Last Updated: 2018-10-26

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

82 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-04-30

Study Completion Date

2015-11-30

Brief Summary

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Goal of the present study is to evaluate the efficacy of Myoelectrically-controlled Functional Electrical Stimulation (MeCFES) for the rehabilitation of upper limb in post-stroke patients. MeCFES-assisted rehabilitation will be compared with usual care rehabilitation of upper limb. It is hypothesized that that applying MeCFES in rehabilitation to assist normal arm movements during rehabilitation of the upper limb in persons with stroke will improve the movement quality and success and thus induce recovery at the body functions level (impairment) and the activity level (disability) of the International Classification of Function (ICF) superior to that induced by usual care rehabilitation.

Detailed Description

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Conditions

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Stroke

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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MeCFES

25 daily sessions (45 minutes each) of MeCFES-assisted task-oriented upper limb rehabilitation

Group Type EXPERIMENTAL

MeCFES-assisted task-oriented upper limb rehabilitation

Intervention Type DEVICE

Control

25 daily sessions (45 minutes each) of usual care task-oriented upper limb rehabilitation

Group Type ACTIVE_COMPARATOR

Usual Care task-oriented upper limb rehabilitation

Intervention Type OTHER

Interventions

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MeCFES-assisted task-oriented upper limb rehabilitation

Intervention Type DEVICE

Usual Care task-oriented upper limb rehabilitation

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Hemiplegia/hemiparesis due to a first ischemic or haemorrhagic stroke
* at least 1 month post-stroke
* willingness to participate the project
* minimum voluntary muscle activation of shoulder flexors (\>1 Manual Muscle Test)
* passive Range of Motion (ROM) of the shoulder and elbow of more than 90°

Exclusion Criteria

* epilepsy
* severe spasticity at upper limb (\>= 3 Ashworth scale)
* implanted electronic device
* respiratory insufficiency
* pregnancy
* peripheral neuropathies
* cutaneous ulcers at the stimulation zone
* other use of FES on the upper limb
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istituto Di Ricerche Farmacologiche Mario Negri

OTHER

Sponsor Role collaborator

Fondazione Don Carlo Gnocchi Onlus

OTHER

Sponsor Role lead

Responsible Party

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Maurizio Ferrarin

Dr.Eng., Ph.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Maurizio Ferrarin, PhD

Role: PRINCIPAL_INVESTIGATOR

Fondazione Don Carlo Gnocchi Onlus

References

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van der Lee JH, Roorda LD, Beckerman H, Lankhorst GJ, Bouter LM. Improving the Action Research Arm test: a unidimensional hierarchical scale. Clin Rehabil. 2002 Sep;16(6):646-53. doi: 10.1191/0269215502cr534oa.

Reference Type BACKGROUND
PMID: 12392340 (View on PubMed)

Fugl-Meyer AR, Jaasko L, Leyman I, Olsson S, Steglind S. The post-stroke hemiplegic patient. 1. a method for evaluation of physical performance. Scand J Rehabil Med. 1975;7(1):13-31.

Reference Type BACKGROUND
PMID: 1135616 (View on PubMed)

Wessels R, de Witte L, Andrich R, Ferrario M, Persson J, Oberg B, Oortwijn W, VanBeekum T, Lorentsen Ã. IPPA, a user-centered approach to assess effectiveness of assistive technology provision. Technol Disabil. 2000;13:105-15

Reference Type BACKGROUND

Kennedy CA, Beaton DE, Solway S, McConnell S, Bombardier C. Disabilities of the Arm, Shoulder and Hand (DASH). The DASH and QuickDASH Outcome Measure User's Manual, Third Edition. Toronto, Ontario: Institute for Work & Health, 2011.

Reference Type BACKGROUND

Other Identifiers

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RISES

Identifier Type: -

Identifier Source: org_study_id

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