Investigation of Genetic Disease Marker Associated With Spontaneous Haemorrhagic Stroke Complicating Severe Pre-eclampsia in Pregnancy

NCT ID: NCT05121415

Last Updated: 2023-03-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-10-23

Study Completion Date

2023-01-20

Brief Summary

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To search for a genetic marker of hemorrhagic stroke complicating severe eclampsia, a single nucleotide polymorphism (SNP) analysis of DNA obtained from the peripheral blood of patients with hemorrhagic stroke and normal control will be performed.

Detailed Description

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Detailed Description:

Unrelated Korean subjects who have Spontaneous hemorrhagic stroke complicating severe eclampsia in pregnancy were recruited in the current study. Genotyping for various SNP associated due to the linkage disequilibrium patterns is to be performed. Genotypes would be statistically compared between patients with hemorrhagic stroke and normal control subjects free of hemorrhagic stroke

Conditions

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Hemorrhagic Stroke Eclampsia

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Experimental group:

patients with hemorrhagic stroke complicating severe pre-eclampsia in pregnancy

SNP analysis of the DNA

Intervention Type GENETIC

SNP analysis of the DNA obtained from peripheral blood sample

Control group

patients without hemorrhagic stroke complicating severe pre-eclampsia in pregnancy

SNP analysis of the DNA

Intervention Type GENETIC

SNP analysis of the DNA obtained from peripheral blood sample

Interventions

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SNP analysis of the DNA

SNP analysis of the DNA obtained from peripheral blood sample

Intervention Type GENETIC

Eligibility Criteria

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Inclusion Criteria

-patients with hemorrhagic stroke complicating severe eclampsia in pregnancy

Exclusion Criteria

patients without hemorrhagic stroke complicating severe eclampsia in pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Asfendiyarov Kazakh National Medical University

OTHER

Sponsor Role lead

Responsible Party

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Ildar Fakhradiyev

Head of the Laboratory of Experimental Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Aygul Terlikbayeva, PhD

Role: STUDY_DIRECTOR

JSC "Scientific center of obstetrics, gynecology and perinatology"

Locations

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Hospital

Almaty, , Kazakhstan

Site Status

Countries

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Kazakhstan

Other Identifiers

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1189

Identifier Type: -

Identifier Source: org_study_id

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