Effects of Photobiomodulation on Postoperative Pain After Primary Endodontic Therapy in Molars With Symptomatic Apical Periodontitis

NCT ID: NCT05032612

Last Updated: 2023-03-24

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-09-16

Study Completion Date

2022-03-16

Brief Summary

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The purpose of this study is to evaluate the effects of photobiomodulation (PBM) on postoperative pain after endodontic treatment in mandibular molar teeth diagnosed with symptomatic apical periodontitis.

Detailed Description

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Conditions

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Postoperative Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Participants

Study Groups

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PBM Therapy

Group Type EXPERIMENTAL

PBM Therapy

Intervention Type DEVICE

After the endodontic treatment, PBM therapy will be performed using a 660 nm diode laser (SiroLaser Advance Plus, Dentsply Sirona Inc, Charlotte, NC, USA), with an 8mm tip diameter.The laser tip will be placed on the following external surfaces in a contact mode: mesiobuccal, distobuccal, mesiolingual and distolingual . The power output of the laser will be 50mW and will be verified by Power Meter (PM600 Power/Energy meter, Molectron Detector Inc, Portland, OR, USA). Each site will be irradiated for 25 s with an energy density of 10 J/cm2 .

PBM Sham

Group Type SHAM_COMPARATOR

PBM Sham

Intervention Type DEVICE

For the PBM sham similar procedure as PBM therapy will be performed without activating the laser.

Interventions

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PBM Therapy

After the endodontic treatment, PBM therapy will be performed using a 660 nm diode laser (SiroLaser Advance Plus, Dentsply Sirona Inc, Charlotte, NC, USA), with an 8mm tip diameter.The laser tip will be placed on the following external surfaces in a contact mode: mesiobuccal, distobuccal, mesiolingual and distolingual . The power output of the laser will be 50mW and will be verified by Power Meter (PM600 Power/Energy meter, Molectron Detector Inc, Portland, OR, USA). Each site will be irradiated for 25 s with an energy density of 10 J/cm2 .

Intervention Type DEVICE

PBM Sham

For the PBM sham similar procedure as PBM therapy will be performed without activating the laser.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Posterior mandibular molars
* No previous root canal therapy on the tooth in question
* Able to complete the endodontic treatment in one visit

Exclusion Criteria

* Maxillary teeth, mandibular anteriors and premolars
* Infection (swelling, sinus tract) on the tooth in question
* Periodontal disease on the tooth in question
* Dental trauma
* Crown/ root fractures
* Systemic diseases
* Immunocompromised patients
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The University of Texas Health Science Center, Houston

OTHER

Sponsor Role lead

Responsible Party

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Timothy Kirkpatrick

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ryne Jackson, DMD

Role: PRINCIPAL_INVESTIGATOR

The University of Texas Health Science Center, Houston

Locations

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The University of Texas Health Science Center at Houston

Houston, Texas, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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HSC-DB-21-0579

Identifier Type: -

Identifier Source: org_study_id

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