Effect of Root Canal Treatment (Versus no Treatment) for Patients With Tooth Infections and Toothaches
NCT ID: NCT01870973
Last Updated: 2015-06-18
Study Results
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View full resultsBasic Information
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COMPLETED
NA
108 participants
INTERVENTIONAL
2013-03-31
2014-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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root canal treatment
root canal treatment, anesthesia with 2% lidocaine with 1:100,000 epinephrine, pain medication (1000 mg acetaminophen and 600 mg ibuprofen every 6 hours)five day supply, antibiotic (500 mg penicillin, if allergic 300 mg clindamycin)
root canal treatment, anesthesia, pain medications, and antibiotic
Root canal treatment is the intervention (no initial treatment versus initial treatment). We are not studying a drug or device.
no root canal treatment
no root canal treatment, anesthesia with 2% lidocaine with 1:100,000 epinephrine, pain medication (1000 mg acetaminophen and 600 mg ibuprofen every 6 hours)five day supply, antibiotic (500 mg penicillin if allergic 300 mg clindamycin)
no root canal treatment, anesthesia, pain medications, and antibiotic
Interventions
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root canal treatment, anesthesia, pain medications, and antibiotic
Root canal treatment is the intervention (no initial treatment versus initial treatment). We are not studying a drug or device.
no root canal treatment, anesthesia, pain medications, and antibiotic
Eligibility Criteria
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Inclusion Criteria
* in good health (ASA classification I or II)
* able to give informed consent
* infected tooth with toothache (symptomatic tooth with pulpal necrosis)
Exclusion Criteria
* history of significant medical problems (ASA classification III or greater)
* angioedema or bronchospastic reactivity to aspirin or other NSAIDs
* pregnant or lactating
* inability to give informed consent
18 Years
ALL
No
Sponsors
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Ohio State University
OTHER
Responsible Party
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Melissa Drum
Associate Professor
Locations
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The Ohio State University College of Dentistry, Postle Hall
Columbus, Ohio, United States
Countries
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References
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Houck V, Reader A, Beck M, Nist R, Weaver J. Effect of trephination on postoperative pain and swelling in symptomatic necrotic teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000 Oct;90(4):507-13. doi: 10.1067/moe.2000.108960.
Nist E, Reader A, Beck M. Effect of apical trephination on postoperative pain and swelling in symptomatic necrotic teeth. J Endod. 2001 Jun;27(6):415-20. doi: 10.1097/00004770-200106000-00013.
Henry M, Reader A, Beck M. Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth. J Endod. 2001 Feb;27(2):117-23. doi: 10.1097/00004770-200102000-00016.
Nusstein JM, Reader A, Beck M. Effect of drainage upon access on postoperative endodontic pain and swelling in symptomatic necrotic teeth. J Endod. 2002 Aug;28(8):584-8. doi: 10.1097/00004770-200208000-00005.
Mickel AK, Wright AP, Chogle S, Jones JJ, Kantorovich I, Curd F. An analysis of current analgesic preferences for endodontic pain management. J Endod. 2006 Dec;32(12):1146-54. doi: 10.1016/j.joen.2006.07.015. Epub 2006 Oct 19.
Wells LK, Drum M, Nusstein J, Reader A, Beck M. Efficacy of Ibuprofen and ibuprofen/acetaminophen on postoperative pain in symptomatic patients with a pulpal diagnosis of necrosis. J Endod. 2011 Dec;37(12):1608-12. doi: 10.1016/j.joen.2011.08.026. Epub 2011 Oct 1.
Other Identifiers
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root canal versus no treatment
Identifier Type: -
Identifier Source: org_study_id
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