Psychogenic and Neurogenic Components in Patients With Psychogenic or Neuropathic Pruritus

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-08-25

Study Completion Date

2022-07-08

Brief Summary

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Scientific research on pruritus is in intensive development, with significant advances in understanding its pathophysiology. The causes of pruritus are very huge; they can be classified into different categories; we can find dermatological causes, systemic causes, neuropathic or neurological causes, psychogenic or even idiopathic causes.

The diagnosis of psychogenic pruritus is often over stated, when no cause is found; therefore, it is important to see what is really relieving from psychic so as not to over-diagnose and adopt a therapy more in line with the real problem of the patient. In daily practice, it seems to have a tendency to separate psychogenic and neurogenic etiologies in the diagnosis of neuropathic or psychogenic pruritus.

In the case of patients with psychogenic pruritus and neuropathic pruritus, no study has attempted to study the respective part of psychogenic and neurogenic components. Consequently, it would therefore be interesting to assess the areas of superposition and distinction of neuropathic and psychogenic pruritus.

The aim of this pilot study is to assess the psychogenic and neurogenic components of psychogenic pruritus and neuropathic pruritus in order to improve understanding of the mechanism and therefore their management.

The main objective of this study is to highlight the differences and the potential common characteristics between psychogenic and neuropathic pruritus in order to improve the differential diagnosis between these two pathologies.

The secondary objective of this study is to describe the psychogenic and neurogenic characteristics of psychogenic and neuropathic pruritus.

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Detailed Description

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PruriNeuro : Non-interventional single-center prospective study organized and practiced on humans for the development of medical knowledge, in which the data are obtained by validated questionnaires.

The duration of participation is estimated at 1 hour.

Questionnaires used :

* Critères diagnostiques du prurit psychogène (Diagnosis criteria of functional itch disorder or psychogenic pruritus, from the French psychodermatology group)
* NP5 questionnaire
* Questionnaire de Brest
* HADS
* TAS-20
* DN4i

Conditions

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Pruritus Psychogenic Skin Disease Neuropathic Pain Itch

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Patients with Psychogenic pruritus

Questionnaires

Intervention Type OTHER

Evaluation of the Psychogenic and Neurogenic Components using questionnaires

Patients with Neuropathic Pruritus

Questionnaires

Intervention Type OTHER

Evaluation of the Psychogenic and Neurogenic Components using questionnaires

Interventions

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Questionnaires

Evaluation of the Psychogenic and Neurogenic Components using questionnaires

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Major (\> 18 years old)
* Diagnosis of psychogenic pruritus or neuropathic pruritus made in consultation, in day hospital or in hospital, within the dermatology department at the CHRU de Brest
* Able to understand and agree to sign the information and non-opposition notice
* No opposition of the patient

Exclusion Criteria

* Patient under legal protection (guardianship, curatorship)
* Minor (\<18 years old)
* Acute or chronic condition which could limit the patient's ability to the study's participation
* Inability to understand and sign the information and non-opposition notice
* Refusal to give no opposition

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No