Elaboration of a Pre-surgery Mapping Protocol of Primary Motor Cortex, Prior to an Implementation of a Stimulation of Primary Motor Cortex for Patients With Deafferentiation of Brachial Plexus Pain
NCT ID: NCT01104506
Last Updated: 2010-12-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
NA
13 participants
INTERVENTIONAL
2010-04-30
2010-09-30
Brief Summary
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The principal endpoints is to identify and test the reliability of a muscular marker for which the cortical representation is localized immediately next to the superior member area. Several muscles of cephalic, cervical and chest area will be investigate.
The methods used will be mono-shock transcranial magnetic stimulation (mTMS) and functional MRI.
Concerning mTMS, several methods will be tested: best position on the scalp, realisation of outputs maps with extreme points average method, with mass center method.
Concerning fMRI studies, the above paradigms will be checked: imaginary movements of hand, blow up and down abdomen, eyes winking.
Statistical tests will confirm the best muscle candidate and will permit to evaluate the reliability of the method.
Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
DIAGNOSTIC
NONE
Study Groups
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Painless plexus
Patient with a painless avulsion of brachial plexus
fMRI
mTMS
Healthy
Healthy volunteers
fMRI
mTMS
Painful plexus
Patient with a painful avulsion of brachial plexus
fMRI
mTMS
Interventions
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fMRI
mTMS
Eligibility Criteria
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Inclusion Criteria
* For group 1 "painful BPA": consulting to the Nantes'UH for pain of BPA, EVA≥4, neurological deficiency partial or total
* For group 2 "painless BPA": EVA\<4, neurological deficiency partial or total, matching with group 1 on the neurological deficiency
* For group 3 "Healthy": matching with group 1 on age ±10 years
Exclusion Criteria
* Medical history of epilepsy
* Pregnant women
* Contra-indication to MRI
18 Years
ALL
Yes
Sponsors
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Nantes University Hospital
OTHER
Responsible Party
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Nantes University Hospital
Locations
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Nantes UH
Nantes, , France
Countries
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Other Identifiers
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2010-A00141-38
Identifier Type: OTHER
Identifier Source: secondary_id
BRD 10/2-A
Identifier Type: -
Identifier Source: org_study_id