Effect of Frankincense Extract Gel on Non-Surgical Treatment of Chronic Periodontitis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-04-01

Study Completion Date

2022-03-31

Brief Summary

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This study will evaluate the effect of the subgingival application of Frankincense extract gel as an adjunct to scaling and root planning (SRP) in chronic periodontitis.

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Detailed Description

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: twenty patients will be randomly selected and equally divided into Group I: will receive SRP only, group II: will receive SRP and Frankincense extract the gel. Subgingival application of Frankincense extract gel will be performed following initial SRP )day 1) and at 7, and 14 days. Clinical measurements included pocket depth (PD), bleeding on probing (BOP), and clinical attachment level (CAL). Real-time PCR was carried out to determine the effect of the treatment on Porphyromonas gingivalis (Pg). Clinical measurements and Plaque samples for PCR were recorded at baseline (before treatment), one, and three months after treatment.

Conditions

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Chronic Periodontitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

twenty patients will be randomly be selected and equally divided into Group I: will receive SRP only, group II: will receive SRP and Frankincense extract the gel. Subgingival application of Frankincense extract gel will be performed following initial SRP )day 1) and at 7, and 14 days.

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Placebo group

ten patients with sites suffering from mild chronic periodontitis sites will be treated with scaling and root planing (SRP) only

Group Type PLACEBO_COMPARATOR

scaling and root planing

Intervention Type PROCEDURE

will receive scaling and root planing only

test group

Ten patients with sites suffering from mild chronic periodontitis. sites will be treated with scaling and root planing (SRP) and subgingival application of Frankincense extract gel

Group Type ACTIVE_COMPARATOR

scaling and root planing

Intervention Type PROCEDURE

will receive scaling and root planing only

Frankincense extract gel natural herbal product

Intervention Type PROCEDURE

will receive Scaling and root planing then. Subgingival application of Frankincense extract gel

Interventions

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scaling and root planing

will receive scaling and root planing only

Intervention Type PROCEDURE

Frankincense extract gel natural herbal product

will receive Scaling and root planing then. Subgingival application of Frankincense extract gel

Intervention Type PROCEDURE

Other Intervention Names

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Scaling and root planing

Eligibility Criteria

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Inclusion Criteria

* systemically healthy patients were selected
* patients who had not received any medications for the previous six months that may interfere with periodontal tissue health or healing.
* Patients should demonstrate their ability to maintain good oral hygiene