Virtual Environment to Aid Cognitive Stimulation of Elderly People With Early Alzheimer's

NCT ID: NCT04919005

Last Updated: 2021-06-09

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 34 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2016-07-01
• Study Completion Date: 2017-07-20

Brief Summary

This research was carried out with the objective of verifying the possibility of intervention through cognitive training protocols to assist in the stimulation of neurons and to delay the degradation resulting from Alzheimer's disease in its initial phase. The specific objective of this research was to develop and validate a virtual environment of games (called SorrisoTur) that allows the intervention of cognitive training.

Detailed Description

SorrisoTur encompasses cognitive training concepts and protocols in playful situations, which were coded in the form of 2D mini-games that are run on a computer connected to the Web, and designed to stimulate cognitive domains, such as memory, executive functions, spatial-visual skills, language (expression, comprehension, reading, and writing) and personality/behavior. For the comparison of results, three groups were created; one group of elderly people with Alzheimer's disease at an early stage, one group formed by healthy elderly, and another group with young people and applied Mini-Mental State Examination (MMSE) and Wechsler Intelligence Scale for Adults (WAIS-III) before and after of interventions with the games.

Conditions

Alzheimer Disease

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: NONE

Study Groups

Healthy elderly people

Twelve healthy elderly people. Each participant underwent a pre-test, the intervention with a Virtual Environment, and a post-test.

Group Type: EXPERIMENTAL

Virtual Environment

Intervention Type: OTHER

The Virtual Environment was called SorrisoTur and consists of 10 mini-games with difficulty levels in a limited number of cities and mini-games distributed in a thematic scenario of the map of Brazil. The virtual environment consists of the cognitive training mini-games within a theme for all screens, mini-games, and information. The interventions with the Virtual Environment were administered in periods of one hour, twice a week, for a month.

Elderly people with Alzheimer's in the initial phase

Seven elderly people with Alzheimer's in the initial phase. Each participant underwent a pre-test, the intervention with a Virtual Environment, and a post-test.

Group Type: EXPERIMENTAL

Virtual Environment

Intervention Type: OTHER

The Virtual Environment was called SorrisoTur and consists of 10 mini-games with difficulty levels in a limited number of cities and mini-games distributed in a thematic scenario of the map of Brazil. The virtual environment consists of the cognitive training mini-games within a theme for all screens, mini-games, and information. The interventions with the Virtual Environment were administered in periods of one hour, twice a week, for a month.

Healthy young people

Fifteen healthy young people. Each participant underwent a pre-test, the intervention with a Virtual Environment, and a post-test.

Group Type: EXPERIMENTAL

Virtual Environment

Intervention Type: OTHER

The Virtual Environment was called SorrisoTur and consists of 10 mini-games with difficulty levels in a limited number of cities and mini-games distributed in a thematic scenario of the map of Brazil. The virtual environment consists of the cognitive training mini-games within a theme for all screens, mini-games, and information. The interventions with the Virtual Environment were administered in periods of one hour, twice a week, for a month.

Interventions

Virtual Environment

The Virtual Environment was called SorrisoTur and consists of 10 mini-games with difficulty levels in a limited number of cities and mini-games distributed in a thematic scenario of the map of Brazil. The virtual environment consists of the cognitive training mini-games within a theme for all screens, mini-games, and information. The interventions with the Virtual Environment were administered in periods of one hour, twice a week, for a month.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• People with physical or psychological conditions allow interacting with digital games;
• Elderly over 60 years with mild Alzheimer;
• Seniors over 60 Healthy;
• Healthy Youth;

Exclusion Criteria

• People without physical or psychological conditions allow interacting with digital games;
• Elderly people over 60 years old who have any type of dementia other than Alzheimer, or moderate or severe Alzheimer;

• Minimum Eligible Age: 19 Years
• Maximum Eligible Age: 99 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Mogi das Cruzes

OTHER

Sponsor Role: lead

Responsible Party

Terigi Augusto Scardovelli

Associate Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Marcia A Bissaco, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Mogi das Cruzes

Locations

Terigi Augusto Scardovelli

Mogi das Cruzes, São Paulo, Brazil

Countries

Brazil

Other Identifiers

CAAE: 54290416.9.0000.5497

Identifier Type: -

Identifier Source: org_study_id