Effect of Exergaming Program Versus Neuromuscular Exercise in Elderly People With Motor Cognitive Risk Syndrome

NCT ID: NCT07045259

Last Updated: 2026-01-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-12-25

Study Completion Date

2026-06-30

Brief Summary

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The primary aim of our study is to compare the effects of neuromuscular exercise training versus structured exergaming program on locomotor and cognitive functions in elderly individuals with Motor Cognitive Risk (MCR), which defines the transition state between typical aging and dementia and mild cognitive impairment. This study aims to present for the first time the effects of neuromuscular exercise training and exergaming program on locomotor and cognitive functions in elderly individuals with MCR with comparative results.

Detailed Description

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Conditions

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Motoric Cognitive Risk Syndrome Elderly (People Aged 65 or More) Geriatric Patient Exergaming Neuromuscular Exercise

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
Patients who meet the inclusion criteria will be randomized into three treatment groups, structured exergaming and neuromuscular exercise training and control group with a 1:1 block allocation. Randomization will be performed by a researcher not involved in the study using a website (www.randomization.com). Interventions and assessments will be administered by physiotherapists. After the end of treatment, both groups will be re-evaluated using the same procedures.

Study Groups

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The Neuromuscular Exercise Group

Group Type ACTIVE_COMPARATOR

Exergaming Exercise Training

Intervention Type OTHER

In our study, Xbox One Kinect game console and Kinect sensor will be used within the scope of Exergaming. Exergaming program will be carried out in groups of 2 people for 45 minutes/ 2 days/ 8 weeks. It will consist of warm-up, loading and cooling phases. The games to be used for the Exergaming program were selected from games that include locomotor and cognitive repetitive tasks. The selected exergames involve repetitive locomotor and cognitive tasks. Piano step will be utilized during the warm-up for its rhythm-based movement patterns. For the conditioning phase, lower extremity exercises will include Reflex Ridge, River Rush, and Rallyball (Kinect Adventures), while upper extremity exercises will consist of Bowling, Table Tennis, Swimming (Kinect Sports), and Fruit Ninja. A progressive training approach will be followed, with game difficulty levels increasing incrementally as the sessions advance.

Exergaming Group

Group Type ACTIVE_COMPARATOR

The Neuromuscular Exercise Training program

Intervention Type OTHER

The Neuromuscular Exercise Training program will be carried out in groups of 2 people for 45 minutes/2 days/8 weeks. The exercise program will consist of warm-up, loading and cooling phases. The warm-up phase will consist of flexibility exercises, mini squat and roll down etc. exercises to prepare the individual for exercise. The loading phase will consist of a cognitive-based neuromuscular exercise program aiming to provide stabilization, increase in balance, neuroplasticity and motor control and is planned to include strengthening exercises, stabilization exercises, balance-proprioceptive exercises and neuromuscular control exercise training with visual feedback. The exercises will progress gradually from easy to difficult with increasing repetition and set numbers.

Control Group

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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The Neuromuscular Exercise Training program

The Neuromuscular Exercise Training program will be carried out in groups of 2 people for 45 minutes/2 days/8 weeks. The exercise program will consist of warm-up, loading and cooling phases. The warm-up phase will consist of flexibility exercises, mini squat and roll down etc. exercises to prepare the individual for exercise. The loading phase will consist of a cognitive-based neuromuscular exercise program aiming to provide stabilization, increase in balance, neuroplasticity and motor control and is planned to include strengthening exercises, stabilization exercises, balance-proprioceptive exercises and neuromuscular control exercise training with visual feedback. The exercises will progress gradually from easy to difficult with increasing repetition and set numbers.

Intervention Type OTHER

Exergaming Exercise Training

In our study, Xbox One Kinect game console and Kinect sensor will be used within the scope of Exergaming. Exergaming program will be carried out in groups of 2 people for 45 minutes/ 2 days/ 8 weeks. It will consist of warm-up, loading and cooling phases. The games to be used for the Exergaming program were selected from games that include locomotor and cognitive repetitive tasks. The selected exergames involve repetitive locomotor and cognitive tasks. Piano step will be utilized during the warm-up for its rhythm-based movement patterns. For the conditioning phase, lower extremity exercises will include Reflex Ridge, River Rush, and Rallyball (Kinect Adventures), while upper extremity exercises will consist of Bowling, Table Tennis, Swimming (Kinect Sports), and Fruit Ninja. A progressive training approach will be followed, with game difficulty levels increasing incrementally as the sessions advance.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Being over 65 years of age
* Having a Barthel Daily Living Activities Index score of ≥ 90
* Having a Mini Mental Status Score (MMSE) of ≥24
* Having the ability to walk with or without a walking aid
* Having a slow walking speed
* Having subjective memory complaints

Exclusion Criteria

* Presence of Dementia
* Major Depression
* Generalized Anxiety Disorder and Delirium
* Parkinson's Disease
* Anemia
* Thyroid Disease
* Vitamin B12 Deficiency
* Malnutrition
* Terminal Illness
* Hearing or Visual Impairment
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istanbul University - Cerrahpasa

OTHER

Sponsor Role lead

Responsible Party

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Gulfidan Tokgoz

İstanbul Üniversitesi-Cerrahpasa

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Gulfidan TOKGÖZ, Lecturer, PhD (c)

Role: PRINCIPAL_INVESTIGATOR

İstanbul University-Cerrahpasa

Saime Nilay ARMAN, Assoc. Prof. Dr.

Role: STUDY_DIRECTOR

İstanbul University-Cerrahpasa

Locations

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Balıkesir Üniversitesi

Balıkesir, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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GULFİDAN TOKGÖZ, Lecturer, PhD (c)

Role: CONTACT

+90552 022 76 32

Saime Nilay ARMAN, Assoc. Prof. Dr.

Role: CONTACT

+90553 455 87 07

Facility Contacts

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GULFİDAN TOKGÖZ, Lecturer, PhD (c)

Role: primary

0552 022 76 32

References

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Reference Type BACKGROUND
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Zirek E, Mustafaoglu R, Cicek A, Ahmed I, Mavromoustakos S. Reliability and Validity of the Turkish Version of the Modified Dynamic Gait Index in the Elderly. Eval Health Prof. 2023 Jun;46(2):135-139. doi: 10.1177/01632787221128311. Epub 2022 Sep 17.

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Alghwiri AA. Reliability and validity of the Arabic Dynamic Gait Index in people poststroke. Top Stroke Rehabil. 2014 Mar-Apr;21(2):173-9. doi: 10.1310/tsr2102-173.

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PMID: 24710977 (View on PubMed)

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Reference Type BACKGROUND
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Corsonello A, Lattanzio F, Pedone C, Garasto S, Laino I, Bustacchini S, Pranno L, Mazzei B, Passarino G, Incalzi RA; Pharmacosurveillance In The Elderly Care Pvc Study Investigators. Prognostic significance of the short physical performance battery in older patients discharged from acute care hospitals. Rejuvenation Res. 2012 Feb;15(1):41-8. doi: 10.1089/rej.2011.1215. Epub 2011 Oct 17.

Reference Type BACKGROUND
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Pavasini R, Guralnik J, Brown JC, di Bari M, Cesari M, Landi F, Vaes B, Legrand D, Verghese J, Wang C, Stenholm S, Ferrucci L, Lai JC, Bartes AA, Espaulella J, Ferrer M, Lim JY, Ensrud KE, Cawthon P, Turusheva A, Frolova E, Rolland Y, Lauwers V, Corsonello A, Kirk GD, Ferrari R, Volpato S, Campo G. Short Physical Performance Battery and all-cause mortality: systematic review and meta-analysis. BMC Med. 2016 Dec 22;14(1):215. doi: 10.1186/s12916-016-0763-7.

Reference Type BACKGROUND
PMID: 28003033 (View on PubMed)

Li Y, Yu N, Zhang C, Song Q, Wang J, Sun W. Test-retest reliability of kinematic and kinetic parameters during dual-task stair walking in the elderly. Front Physiol. 2023 May 9;14:1177159. doi: 10.3389/fphys.2023.1177159. eCollection 2023.

Reference Type BACKGROUND
PMID: 37228826 (View on PubMed)

Casana J, Calatayud J, Silvestre A, Sanchez-Frutos J, Andersen LL, Jakobsen MD, Ezzatvar Y, Alakhdar Y. Knee Extensor Muscle Strength Is More Important Than Postural Balance for Stair-Climbing Ability in Elderly Patients with Severe Knee Osteoarthritis. Int J Environ Res Public Health. 2021 Mar 31;18(7):3637. doi: 10.3390/ijerph18073637.

Reference Type BACKGROUND
PMID: 33807414 (View on PubMed)

Soubra R, Mourad-Chehade F, Chkeir A. Automation of the Timed Up and Go Test Using a Doppler Radar System for Gait and Balance Analysis in Elderly People. J Healthc Eng. 2023 Jun 29;2023:2016262. doi: 10.1155/2023/2016262. eCollection 2023.

Reference Type BACKGROUND
PMID: 37426725 (View on PubMed)

Reis M, Teixeira M, Carvao C, Martins AC. Validity and Reliability of the Self-Administered Timed Up and Go Test in Assessing Fall Risk in Community-Dwelling Older Adults. Geriatrics (Basel). 2025 Apr 29;10(3):62. doi: 10.3390/geriatrics10030062.

Reference Type BACKGROUND
PMID: 40407569 (View on PubMed)

Other Identifiers

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2025/701

Identifier Type: -

Identifier Source: org_study_id

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