Resistance Training Effects on Gut Microbiome and Cardiometabolic Outcomes

NCT ID: NCT04906525

Last Updated: 2023-03-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-05-19

Study Completion Date

2022-09-30

Brief Summary

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The overall objective of this study is to investigate the effects of resistance training on the gut microbiome and cardiometabolic outcomes in adults with overweight and obesity.

Detailed Description

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The overall objective of this study is to investigate the effects of resistance training on the gut microbiome and cardiometabolic outcomes in adults with overweight and obesity.

Conditions

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Exercise Intervention

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Conventional physical activity guidelines

Participants are given recommendations on physical activity guidelines

Group Type OTHER

Conventional physical activity guidelines

Intervention Type OTHER

Participants are given recommendations on physical activity guidelines

Resistance training

Participants will undergo 6 weeks of supervised resistance training

Group Type EXPERIMENTAL

Resistance training

Intervention Type BEHAVIORAL

Participants will undergo 6 weeks of supervised resistance training

Interventions

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Resistance training

Participants will undergo 6 weeks of supervised resistance training

Intervention Type BEHAVIORAL

Conventional physical activity guidelines

Participants are given recommendations on physical activity guidelines

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age 18-35 years
* BMI: 25-45 kg/m2
* Sedentary lifestyle
* Consistent diet patterns
* Weight-stable (\<4 kg change over the last 3 mo)
* Willingness to adhere to resistance training protocol and not change diet
* Non-smoker \>1 year or more

Exclusion Criteria

* Disabilities preventing adherence to resistance training protocol
* Recent start of medications that affect metabolism or appetite
* Antibiotics
* Diabetes
* Drug therapy for coronary artery disease, peripheral artery disease, congestive heart failure, or dyslipidemia
* Uncontrolled hypertension and blood pressure ≥ 180/110
* Gastrointestinal disease and/or bariatric surgery
* Smoking
* Illicit drug use
* Pregnant or lactating individuals
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Missouri-Columbia

OTHER

Sponsor Role lead

Responsible Party

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Jaapna Dhillon

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jaapna Dhillon, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Missouri-Columbia

Locations

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University of Missouri

Columbia, Missouri, United States

Site Status

Countries

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United States

Other Identifiers

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2054484

Identifier Type: -

Identifier Source: org_study_id

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