The Effect of Transcranial Direct Stimulation on Cognitive Functions of Healthy Adults

NCT ID: NCT04873804

Last Updated: 2021-05-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

57 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-10

Study Completion Date

2020-06-10

Brief Summary

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Background: Transcranial direct current stimulation(tDCS) has been used to improve cognitive functions in healthy young adults.

Purpose: To investigate the effect of TDCS application on different cortex regions on cognitive function.

Methods: Sixty individuals aged 18-30 were included in the study. The participants were randomly divided into the left dorsolateral prefrontal cortex (Left DLPFC Group)(n=20), the right posterior parietal cortex (Right PPC Group)(n=20), and the sham group (Sham Group)(n=20). tDCS was applied for 20 minutes on weekdays for 2 weeks. The participants were evaluated in terms of cognitive functions with Neuropsychometric Test Battery before and after treatment.

Detailed Description

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Conditions

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Cognitive Symptom Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

SINGLE

Participants

Study Groups

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LEFT DLPFC

The anode electrode of tDCS was applied to the left DLPFC and the cathode electrode was connected to the contralateral shoulder.

Group Type ACTIVE_COMPARATOR

Transcranial Direct Current Stimulation

Intervention Type OTHER

The intervention protocols were applied using tDCS (Teknofil TESsaNova). All individuals received 2 mA of anodal tDCS for 2 weeks on weekdays. All applications were done in the form of 20-minute sessions.

RİGHT PPC

The anode electrode of tDCS was applied to the right PPC and the cathode electrode was connected to the contralateral shoulder.

Group Type ACTIVE_COMPARATOR

Transcranial Direct Current Stimulation

Intervention Type OTHER

The intervention protocols were applied using tDCS (Teknofil TESsaNova). All individuals received 2 mA of anodal tDCS for 2 weeks on weekdays. All applications were done in the form of 20-minute sessions.

Sham

Placebo was applied by placing the electrodes in the right PPC and left DLPFC without applying current.

Group Type SHAM_COMPARATOR

Transcranial Direct Current Stimulation

Intervention Type OTHER

The intervention protocols were applied using tDCS (Teknofil TESsaNova). All individuals received 2 mA of anodal tDCS for 2 weeks on weekdays. All applications were done in the form of 20-minute sessions.

Interventions

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Transcranial Direct Current Stimulation

The intervention protocols were applied using tDCS (Teknofil TESsaNova). All individuals received 2 mA of anodal tDCS for 2 weeks on weekdays. All applications were done in the form of 20-minute sessions.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* being 18-30 years old

Exclusion Criteria

* alcohol and substance addiction
* previous mental illness
* having mental and cognitive problems
* a history of head trauma
* having cardiovascular disease.
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Medipol University

OTHER

Sponsor Role lead

Responsible Party

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Damla Ören

Physiotherapist MSc

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Miray Budak, PhD

Role: PRINCIPAL_INVESTIGATOR

Medipol University

Lutfu Hanoglu, PhD

Role: STUDY_CHAIR

Medipol University

Locations

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Damla Ören

Istanbul, , Turkey (Türkiye)

Site Status

Medipol Mega Hospital

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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tDCS on DLPFC and PPC

Identifier Type: -

Identifier Source: org_study_id

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