Assessment of the Effect of Restriction on Alimentary AGE in Progression of Chronic Kidney Disease

NCT ID: NCT04827290

Last Updated: 2024-04-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

66 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-08-01

Study Completion Date

2025-09-01

Brief Summary

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Normal-protein and low-AGE through raw or rare proteins diet versus normal-protein and high-AGE diet in stage IIIa-b renal failure patients

Detailed Description

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Conditions

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Kidney Failure, Chronic Chronic Kidney Disease stage3 Chronic Kidney Disease Stage 3B Chronic Kidney Disease Stage 3A (Disorder) Chronic Kidney Disease, Stage 3 (Moderate) Diet Habit

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Normal-protein and low-AGE through raw or rare proteins diet

Normal-protein (0,8g/kg/day) and low-AGE through raw or rare proteins diet during 24 months

Group Type EXPERIMENTAL

Low-AGE diet

Intervention Type BEHAVIORAL

Low-AGE diet during 24 months

Normal-protein and AGE-rich diet

Normal-protein (0,8g/kg/day) and high-AGE through overcooked proteins diet during 24 months

Group Type ACTIVE_COMPARATOR

High-AGE diet

Intervention Type BEHAVIORAL

High-AGE diet during 24 months

Interventions

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Low-AGE diet

Low-AGE diet during 24 months

Intervention Type BEHAVIORAL

High-AGE diet

High-AGE diet during 24 months

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Patients with a grade IIIA-B CKD (GFR with CKD-EPI ≥ 30 mL/min and \< 60mL/min)
* Informed consent signed
* Aged 18 to 89 years

Exclusion Criteria

* Protected adult
* Acute renal failure
* Patient already on a low-AGE diet (\< 1kU AGE/day) following a dietetic consultation
* Current participation in another interventional research
Minimum Eligible Age

18 Years

Maximum Eligible Age

89 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Saint Joseph Saint Luc de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Centre Hospitalier Saint Joseph Saint Luc

Lyon, , France

Site Status

Countries

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France

Central Contacts

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Fanny Doroszewski

Role: CONTACT

0033478618398

Gabrielle Normand, MD

Role: CONTACT

Facility Contacts

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Fanny Doroszewski

Role: primary

0033478618398

Gabrielle Normand, MD

Role: backup

Other Identifiers

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CKD AGE

Identifier Type: -

Identifier Source: org_study_id

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