Muscle Mass or Muscle Function as a prédictive Tools for Outtcomme in Chronic Dialysis Patients

NCT ID: NCT03845452

Last Updated: 2020-09-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

187 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-01

Study Completion Date

2019-01-31

Brief Summary

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Aim of this study is to compare the association of muscle mass and functionality with mortality among chronic haemodialysis

* the involvement of malnutrition inflammation and atherogenesis syndrome (increase in C reactive protein and decrease in serum albumin) on voluntary muscle strength impairment and phyiscal activity.
* the relationship between voluntary muscle strength and mortality
* the relationship between voluntary muscle strength and physical activity

Detailed Description

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Aim of this study is to compare the association of muscle mass and functionality with mortality among chronic haemodialysis

* the involvement of malnutrition inflammation and atherogenesis syndrome (increase in C reactive protein and decrease in serum albumin) on voluntary muscle strength impairment and phyiscal activity.
* the relationship between voluntary muscle strength and mortality
* the relationship between voluntary muscle strength and physical activity

Conditions

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Chrnoic Haemodialysis Patients

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* chronic kidney disease patient with extrarenal replacement therapy by hemodialysis for at least 3 months
* stable clinical condition (absence of infection, stroke or acute decompensation)

Exclusion Criteria

* chronic kidney disease without extrarenal replacement therapy
* history of renal transplantation
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Montpellier

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jean-Paul CRISTOL, Prof

Role: PRINCIPAL_INVESTIGATOR

CHU Lapeyronie, Department of Biochemistry and Hormonology, Montpellier, FRANCE

Locations

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Uhmontpellier

Montpellier, , France

Site Status

Countries

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France

References

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Souweine JS, Pasquier G, Morena M, Patrier L, Rodriguez A, Raynal N, Ohresser I, Benomar R, Hayot M, Mercier J, Gouzi F, Cristol JP. Beyond sarcopenia: frailty in chronic haemodialysis patients. Clin Kidney J. 2024 Jun 29;17(7):sfae069. doi: 10.1093/ckj/sfae069. eCollection 2024 Jul.

Reference Type DERIVED
PMID: 38983653 (View on PubMed)

Other Identifiers

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RECHMPL18_0447

Identifier Type: -

Identifier Source: org_study_id

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