Efficacy of an Intradialysis Combined Training Program on Disability Level and Physical Performance.
NCT ID: NCT02883309
Last Updated: 2016-09-30
Study Results
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Basic Information
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APPROVED_FOR_MARKETING
EXPANDED_ACCESS
2013-11-30
2014-03-31
Brief Summary
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Detailed Description
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Materials and methods 18 patients subjected to hemodialysis, whose ages ranged from 54 to 84 (10 women) were included in the study. Nine of these patients participated in a combined training program, which lasted 12 weeks, the training sessions were carried out within each dialysis session, the working session involved a warm-up period, aerobic exercise with pedals, or strength exercises based on free-weight depending on the training stage. The Borg scale and the heart rate reserve were used to control the training intensity. The disability level was evaluated at the beginning and end of the study through the World Health Organization Disability Assessment Schedule II, the six minutes walk test (6MWT), quadriceps strength, Kt/V, serum levels of potassium and creatinine.
Outcomes One subject belonging to the experimental group did not complete the training due to problems in the venous access during the 1st month of training. 8 patients in to the experimental group showed significant improvements in the 6MWT, quadriceps strength and decrease in the level of disability. No changes were observed in the control group. No significant changes were found in the serum levels of potassium and creatine.
Conclusions An Intradialytic physical training program achieved a substantial decrease in the level of disability, and an improvement of aerobic capacity and muscle strength. The study was funded by the extension office of the Austral University of Chile.
Conditions
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Keywords
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Interventions
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intradialytic physical training program
Nine patients participated in the experimental group in a combined training program, which lasted 12 weeks with a frequency of 3 times a week, the training sessions were carried out within each dialysis session during the first 2 hours of the dialysis treatment, the working session involved a warm up period, aerobic exercise with pedals, or strength exercises based on free weight depending on the training stage. The Borg scale and the heart rate reserve were used to control the training intensity. The disability level was evaluated at the beginning and the end of the study through the World Health Organization Disability Assessment Schedule II, the aerobic capacity was evaluated through the six minute walk and the limbs strength was evaluated through a dynamometer.
Eligibility Criteria
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Inclusion Criteria
* Which are between 60-80 years.
* Therapy Dialysis for more than 3 months period.
* Submit 24 or more points on the Mini-mental state test.
Exclusion Criteria
* Dyspnea at rest.
* Hospitalized one month before surgery.
* Diseases Cerebrovascular transient ischemic attacks.
* Lower limb amputation (ankle presence) that this orthopedic prosthesis.
* Syndrome Acute coronary.
* Congestive heart failure or severe pneumonia.
* Patients with uncontrolled diabetes pharmacologically or are not within the appropriate standards of glucose for training.
* Patients with uncontrolled hypertension pharmacologically or are not within the proper blood pressure standards for training.
* Persistent Hyperkalemia .
* Angina at rest.
* Lung-disease which results in adverse effects.
50 Years
80 Years
ALL
No
Sponsors
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Nephrocare Portugal
INDUSTRY
Universidad Austral de Chile
OTHER
Responsible Party
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Principal Investigators
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Paula I Moscoso, Mph PTh
Role: STUDY_CHAIR
Universidad Austral de Chile
Roberto G Mancilla, Student
Role: PRINCIPAL_INVESTIGATOR
Universidad Austral de Chile
Cesar E Gonzalez, Student
Role: PRINCIPAL_INVESTIGATOR
Universidad Austral de Chile
Manuel Monrroy, Msc(c) PTh
Role: STUDY_DIRECTOR
Universidad Austral de Chile
Lizzy Orellana, MD
Role: STUDY_DIRECTOR
Universidad Austral de Chile
References
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Johansen KL. Physical functioning and exercise capacity in patients on dialysis. Adv Ren Replace Ther. 1999 Apr;6(2):141-8. doi: 10.1016/s1073-4449(99)70032-4.
de Lima MC, Cicotoste Cde L, Cardoso Kda S, Forgiarini LA Jr, Monteiro MB, Dias AS. Effect of exercise performed during hemodialysis: strength versus aerobic. Ren Fail. 2013;35(5):697-704. doi: 10.3109/0886022X.2013.780977. Epub 2013 Apr 8.
Ribeiro R, Coutinho GL, Iuras A, Barbosa AM, Souza JA, Diniz DP, Schor N. Effect of resistance exercise intradialytic in renal patients chronic in hemodialysis. J Bras Nefrol. 2013 Jan-Mar;35(1):13-9. doi: 10.5935/01012800.20130003. English, Portuguese.
Giannaki CD, Stefanidis I, Karatzaferi C, Liakos N, Roka V, Ntente I, Sakkas GK. The effect of prolonged intradialytic exercise in hemodialysis efficiency indices. ASAIO J. 2011 May-Jun;57(3):213-8. doi: 10.1097/MAT.0b013e318215dc9e.
KARVONEN MJ, KENTALA E, MUSTALA O. The effects of training on heart rate; a longitudinal study. Ann Med Exp Biol Fenn. 1957;35(3):307-15. No abstract available.
American College of Sports Medicine Position Stand. The recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness, and flexibility in healthy adults. Med Sci Sports Exerc. 1998 Jun;30(6):975-91. doi: 10.1097/00005768-199806000-00032.
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Mercer TH, Naish PF, Gleeson NP, Wilcock JE, Crawford C. Development of a walking test for the assessment of functional capacity in non-anaemic maintenance dialysis patients. Nephrol Dial Transplant. 1998 Aug;13(8):2023-6. doi: 10.1093/ndt/13.8.2023.
ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002 Jul 1;166(1):111-7. doi: 10.1164/ajrccm.166.1.at1102. No abstract available.
DePaul V, Moreland J, Eager T, Clase CM. The effectiveness of aerobic and muscle strength training in patients receiving hemodialysis and EPO: a randomized controlled trial. Am J Kidney Dis. 2002 Dec;40(6):1219-29. doi: 10.1053/ajkd.2002.36887.
Headley S, Germain M, Mailloux P, Mulhern J, Ashworth B, Burris J, Brewer B, Nindl BC, Coughlin M, Welles R, Jones M. Resistance training improves strength and functional measures in patients with end-stage renal disease. Am J Kidney Dis. 2002 Aug;40(2):355-64. doi: 10.1053/ajkd.2002.34520.
Parsons TL, Toffelmire EB, King-VanVlack CE. Exercise training during hemodialysis improves dialysis efficacy and physical performance. Arch Phys Med Rehabil. 2006 May;87(5):680-7. doi: 10.1016/j.apmr.2005.12.044.
Redelmeier DA, Bayoumi AM, Goldstein RS, Guyatt GH. Interpreting small differences in functional status: the Six Minute Walk test in chronic lung disease patients. Am J Respir Crit Care Med. 1997 Apr;155(4):1278-82. doi: 10.1164/ajrccm.155.4.9105067.
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Garin O, Ayuso-Mateos JL, Almansa J, Nieto M, Chatterji S, Vilagut G, Alonso J, Cieza A, Svetskova O, Burger H, Racca V, Francescutti C, Vieta E, Kostanjsek N, Raggi A, Leonardi M, Ferrer M; MHADIE consortium. Validation of the "World Health Organization Disability Assessment Schedule, WHODAS-2" in patients with chronic diseases. Health Qual Life Outcomes. 2010 May 19;8:51. doi: 10.1186/1477-7525-8-51.
Related Links
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Estudio piloto sobre entrenamiento físico durante hemodiálisis
Whodas II Acta Psiquiatrica
Intradialytic versus home based exercise training in hemodialysis patients: a randomised controlled trial
Efeitos do exercício físico durante a hemodiálise em indivíduos com insuficiência renal crônica: uma revisão
Other Identifiers
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33-2013
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
Universidad Austral de Chile
Identifier Type: -
Identifier Source: org_study_id