Antibiotic Prescribing Behavior Among French Intensivist: Construction and Validation of a Questionnaire

NCT ID: NCT04820062

Last Updated: 2021-08-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

115 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-08-31

Study Completion Date

2022-09-01

Brief Summary

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Antibiotic resistance is a major threat in modern medicine. Overuse of antibiotics is an important driver of antibiotic resistance. However, some authors have shown that up to 50% of antibiotic treatments in critically ill patients are inappropriate, mostly because they are used in patients with non-bacterial infections.

In order to improve antibiotic use, several antibiotic stewardship programs have been implemented worldwide. However, only few of them have taken into account the determinants of prescribing behaviors. Yet, these determinants have been shown to play a role among general practitioners of hospital doctors. Nevertheless, none of these factors have been studied among intensivists.

The current project represent phase 1 of the study : construction and validation of a questionnaire.

Detailed Description

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Antibiotic resistance is a major threat in modern medicine. Overuse of antibiotics is an important driver of antibiotic resistance. In critical care setting, antibiotic therapies are widely used due to the high number of patients presenting with sepsis. However, some authors have shown that up to 50% of antibiotic treatments in critically ill patients are inappropriate, mostly because they are used in patients with non-bacterial infections.

In order to improve antibiotic use, several antibiotic stewardship programs have been implemented worldwide. However, only few of them have taken into account the determinants of prescribing behaviors. Yet, these determinants have been shown to play a role among general practitioners of hospital doctors. Nevertheless, none of these factors have been studied among intensivists.

The study is designed to investigate social, cultural, contextual and personal factors influencing antibiotic prescribing among French intensivists. The design will consist of three phases:

* Phase 1: construction and validation of a questionnaire
* Phase 2: the questionnaire will be sent to all intensivist, including residents, in France
* Phase 3: qualitative study, based on semi-structured interviews.

The current project represent phase 1 of the study.

Conditions

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Antibiotic Reaction

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Interventions

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Content Validity

For the validity of built, it is generally advisable to include a ratio of 100 participants for 30 questionnaire items. In order to have a suitable questionnaire, we will limit ourselves to 30 items which will be the size of our questionnaire. It was therefore planned to include 100 participants The selection of experts will be based on experience in this area, knowledge and availability. It will be a rescimant physician and an infectious disease doctor. Each expert will be invited in isolation to comment on the items in the questionnaire

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Physicians with predominant intensive care practice
* Resident, with a minimum of two-month experience in the intensive care unit

Exclusion Criteria

* Refusal to participate
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Centre Hospitalier Universitaire de Saint Etienne

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Guillaume THIERY, MD PHD

Role: PRINCIPAL_INVESTIGATOR

CHU ST ETIENNE FRANCE

Locations

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Chu St Etienne

Saint-Etienne, , France

Site Status

Countries

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France

Central Contacts

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GUILLAUME THIERY, MD PHD

Role: CONTACT

(0)4 77 12 78 53 ext. +33

AMANDINE BAUDOT, CRA

Role: CONTACT

(0)4 77 82 94 50 ext. +33

Other Identifiers

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20CH031

Identifier Type: -

Identifier Source: org_study_id

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