Antibiotic Treatment for Pneumonia Caused by Stenotrophomonas Maltophilia in ICU Patients

NCT ID: NCT07052604

Last Updated: 2025-07-04

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 300 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2023-12-15
• Study Completion Date: 2025-09-15

Brief Summary

This study looks at how different antibiotic treatments affect patients in intensive care who have pneumonia caused by the bacteria Stenotrophomonas maltophilia. It compares using one antibiotic versus two antibiotics, and treatment lengths of 7 days versus 14 days, to see which approach helps patients survive better. The study also examines how resistant the bacteria are to antibiotics and how often the pneumonia comes back.

Conditions

Pneumonia, Ventilator-Associated; Stenotrophomonas Maltophilia; Intensive Care Units; Anti-Bacterial Agents; Drug Resistance, Bacterial

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• Adult patients (age ≥ 18 years)
• Hospitalized in Medical Intensive Care Unit between January 1, 2018, and December 31, 2023
• Intubated and mechanically ventilated
• Diagnosed with ventilator-associated pneumonia caused by Stenotrophomonas maltophilia

Exclusion Criteria

• Patients under 18 years old
• Patients who refuse the use of their data for research purposes

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Centre Hospitalier de Saint-Denis

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Centre Hospitalier de Saint-Denis

Saint-Denis, France, France

Site Status: RECRUITING

Countries

France

Facility Contacts

Nolan HASSOLD

Role: primary

coordination.rechercheclinique@ghtpdfr.fr

0142356208

Other Identifiers

0055_STENO

Identifier Type: -

Identifier Source: org_study_id