Bloodstram Infections in ICU. Single Centre Observational Study.

NCT ID: NCT04926935

Last Updated: 2021-06-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

3502 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-01-01

Study Completion Date

2019-12-31

Brief Summary

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Hospital-acquired bloodstream infection (BSI) is serious care problem worldwide associated with significant morbidity and mortality. However, only few nationwide studies have focused on the incidence of BSI, and its results were often inconsistent.

The objective of this study was to analyze bloodstream infections in patients hospitalized in the intensive care unit of the tertiary, university hospital. Special attention was put on the etiology of the infections, the antimicrobial susceptibility/resistance of the isolated pathogens, as well as the incidence of central vein catheters infections in the analyzed population.

Data were collected in the intensive care unit of the Military Institute of Medicine, Warsaw, Poland, between January, 1, 2007 and December, 31, 2019.

Detailed Description

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Conditions

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Bloodstream Infection Antibiotic Resistant Strain Intensive Care Unit

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients hospitalized in the ICU during the study period.

Patients hospitalized in the ICU during the study period with clinically suspected infection.

Microbiological analysis of blood samples.

Intervention Type DIAGNOSTIC_TEST

Microbiological analysis of blood samples collected from the patients with clinically suspected infection.

Interventions

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Microbiological analysis of blood samples.

Microbiological analysis of blood samples collected from the patients with clinically suspected infection.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* all patients hospitalized in the ICU with clinically suspected infection.

Exclusion Criteria

* none.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Military Institute od Medicine National Research Institute

OTHER

Sponsor Role lead

Responsible Party

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Dariusz Tomaszewski

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Dariusz Tomaszewski, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Military Institute od Medicine National Research Institute

Locations

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Department of Anesthesiology and Intensive Therapy

Warsaw, , Poland

Site Status

Countries

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Poland

References

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Garrouste-Orgeas M, Timsit JF, Tafflet M, Misset B, Zahar JR, Soufir L, Lazard T, Jamali S, Mourvillier B, Cohen Y, De Lassence A, Azoulay E, Cheval C, Descorps-Declere A, Adrie C, Costa de Beauregard MA, Carlet J; OUTCOMEREA Study Group. Excess risk of death from intensive care unit-acquired nosocomial bloodstream infections: a reappraisal. Clin Infect Dis. 2006 Apr 15;42(8):1118-26. doi: 10.1086/500318. Epub 2006 Mar 14.

Reference Type RESULT
PMID: 16575729 (View on PubMed)

Laupland KB, Lee H, Gregson DB, Manns BJ. Cost of intensive care unit-acquired bloodstream infections. J Hosp Infect. 2006 Jun;63(2):124-32. doi: 10.1016/j.jhin.2005.12.016. Epub 2006 Apr 18.

Reference Type RESULT
PMID: 16621137 (View on PubMed)

Wilson J, Elgohari S, Livermore DM, Cookson B, Johnson A, Lamagni T, Chronias A, Sheridan E. Trends among pathogens reported as causing bacteraemia in England, 2004-2008. Clin Microbiol Infect. 2011 Mar;17(3):451-8. doi: 10.1111/j.1469-0691.2010.03262.x.

Reference Type RESULT
PMID: 20491834 (View on PubMed)

Nielsen SL, Pedersen C, Jensen TG, Gradel KO, Kolmos HJ, Lassen AT. Decreasing incidence rates of bacteremia: a 9-year population-based study. J Infect. 2014 Jul;69(1):51-9. doi: 10.1016/j.jinf.2014.01.014. Epub 2014 Feb 25.

Reference Type RESULT
PMID: 24576825 (View on PubMed)

de Kraker ME, Jarlier V, Monen JC, Heuer OE, van de Sande N, Grundmann H. The changing epidemiology of bacteraemias in Europe: trends from the European Antimicrobial Resistance Surveillance System. Clin Microbiol Infect. 2013 Sep;19(9):860-8. doi: 10.1111/1469-0691.12028. Epub 2012 Oct 8.

Reference Type RESULT
PMID: 23039210 (View on PubMed)

Goto M, Al-Hasan MN. Overall burden of bloodstream infection and nosocomial bloodstream infection in North America and Europe. Clin Microbiol Infect. 2013 Jun;19(6):501-9. doi: 10.1111/1469-0691.12195. Epub 2013 Mar 8.

Reference Type RESULT
PMID: 23473333 (View on PubMed)

Other Identifiers

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09

Identifier Type: -

Identifier Source: org_study_id

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