Decreased Tongue Strength is Related to Skeletal Muscle Mass in COPD Subjects
NCT ID: NCT04761380
Last Updated: 2021-02-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
51 participants
OBSERVATIONAL
2019-12-01
2020-05-10
Brief Summary
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Dysphagia is frequently observed in subjects with chronic obstructive pulmonary disease (COPD). But tongue strength has not been investigated yet in COPD subjects. The investigators hypothesized that tongue strength is weaker in COPD subjects compared to normal subjects.
Methods:
This was a single-centre, observational, and cross-sectional study. Twenty-seven subjects with COPD and twenty-four age-matched control subjects were enrolled in this study. Isometric tongue strength was measured using a device fitted with a disposable oral balloon probe. The investigators also evaluated handgrip strength, gait speed, and appendicular skeletal muscle mass (ASM) to define participants as having sarcopenia. ASM, fat free mass index (FFMI), and skeletal muscle mass index (SMI) were measured by bioelectrical impedance analysis. Gait speed was measured using the 6-meter walking test. The eating assessment test-10 (EAT-10) was used to diagnose dysphagia.
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Detailed Description
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Conditions
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Study Design
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COHORT
CROSS_SECTIONAL
Study Groups
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stable COPD subjects
balloon-based tongue pressure measurement device
The probe was inflated at a baseline pressure of 19.6 kilopascal (kPa). To measure MTP, the balloon was positioned on the anterior palate with the lips closed. Subjects raised their tongue and compressed the balloon onto the palate with maximal voluntary muscular effort for approximately 7s. The measurement was taken three times with a 1-min interval. The maximum value was recorded as the MTP.
age-matched control subjects subjects who did not have any pulmonary disease
balloon-based tongue pressure measurement device
The probe was inflated at a baseline pressure of 19.6 kilopascal (kPa). To measure MTP, the balloon was positioned on the anterior palate with the lips closed. Subjects raised their tongue and compressed the balloon onto the palate with maximal voluntary muscular effort for approximately 7s. The measurement was taken three times with a 1-min interval. The maximum value was recorded as the MTP.
Interventions
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balloon-based tongue pressure measurement device
The probe was inflated at a baseline pressure of 19.6 kilopascal (kPa). To measure MTP, the balloon was positioned on the anterior palate with the lips closed. Subjects raised their tongue and compressed the balloon onto the palate with maximal voluntary muscular effort for approximately 7s. The measurement was taken three times with a 1-min interval. The maximum value was recorded as the MTP.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Age-matched control subjects who did not have any pulmonary disease.
Exclusion Criteria
* History of stroke disease.
* History of neuromuscular disease.
* Participants who did not have their front teeth.
65 Years
ALL
Yes
Sponsors
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Kindai University
OTHER
Responsible Party
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Locations
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Kindai University Faculty of Medicine
Ōsaka-sayama, Osaka, Japan
Countries
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Other Identifiers
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0414
Identifier Type: -
Identifier Source: org_study_id
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