Interest of a Tongue Strength Measurement in the Screening for Sarcopenia in Hospitalized Elderly Patients

NCT ID: NCT03417609

Last Updated: 2019-04-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

110 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-02-07

Study Completion Date

2019-01-01

Brief Summary

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Sarcopenia is a syndrome characterized by a progressive and generalized loss of skeletal muscle mass, strength and function that increases the risk of physical dependence, impaired quality of life and mortality. This is a major public health problem. Indeed, its prevalence has been estimated at 63.8% for elderly patients hospitalized in acute geriatric unit.

Several methods of sarcopenia screening exist at present. The European Working Group on Sarcopenia in Older People (EWGSOP) proposes to carry out three examinations for the diagnosis of sarcopenia: the Dual-Energy X-ray Absorptiometry (DEXA) test and two motor tests (walking speed and hand test). These measurements have already been evaluated and validated. They are reliable, inexpensive and easily achievable in clinical routine.

Recent studies have shown that decreased muscle mass and / or strength could be associated with dysphagia. Indeed, many muscles of the head and neck are simultaneously solicited for swallowing coordination. This suggests that a reduction in the mass or strength of these muscles could impact the swallowing function. The investigator's hypothesize that loss of lingual muscle strength may be associated with sarcopenia. The study will measure the tongue strength using the Iowa Oral Performance Instrument (IOPI) in a geriatric population with or without sarcopenia.

* Determine the incidence of lingual hypotonia in hospitalized elderly sarcopenia patients.
* To compare the sensitivity, the specificity of the measurement of the force of the tongue with the usual measures proposed by the EWGSOP in the context of screening for sarcopenia.

Detailed Description

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Conditions

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Sarcopenia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Sarcopenia

Elderly patients with sarcopenia

Tongue strength measurement

Intervention Type DEVICE

The Iowa Oral Performance Instrument is a validated device for assessing the strength of the tongue. This involves placing the tip of a tube in the mouth and asking the patient to exert pressure on it.

Blood sampling

Intervention Type PROCEDURE

Blood sampling

Mini Mental State Examination (MMSE)

Intervention Type DIAGNOSTIC_TEST

Also called Folstein test, it is an assessment of the patient cognitive and memory functions. It detects cognitive disorders or dementia. The MMSE is quickly realizable and explores several cognitive functions through 30 questions divided into 7 items.

Minimal nutritional assessment (MNA-SF)

Intervention Type DIAGNOSTIC_TEST

The minimal nutritional assessment - short form is a simple, non - invasive and validated scale for the detection of malnutrition in the elderly patient.

Dual-energy x-ray absorptiometry (DEXA)

Intervention Type DIAGNOSTIC_TEST

Dual-energy x-ray absorptiometry (DEXA) is the imaging technique recommended for the diagnosis of sarcopenia.

Dynamometer (Hand grip )

Intervention Type DEVICE

By placing a dynamometer in the patient's hand and asking him to apply maximum pressure to it, the muscular strength of the extremities of the limbs is estimated.

Walking speed

Intervention Type DIAGNOSTIC_TEST

Walking speed evaluates the muscular performance. The seated patient must get up and walk a distance of 6 meters as quickly as possible without the help of a third party.

Control

Elderly patients without sarcopenia

Tongue strength measurement

Intervention Type DEVICE

The Iowa Oral Performance Instrument is a validated device for assessing the strength of the tongue. This involves placing the tip of a tube in the mouth and asking the patient to exert pressure on it.

Blood sampling

Intervention Type PROCEDURE

Blood sampling

Mini Mental State Examination (MMSE)

Intervention Type DIAGNOSTIC_TEST

Also called Folstein test, it is an assessment of the patient cognitive and memory functions. It detects cognitive disorders or dementia. The MMSE is quickly realizable and explores several cognitive functions through 30 questions divided into 7 items.

Minimal nutritional assessment (MNA-SF)

Intervention Type DIAGNOSTIC_TEST

The minimal nutritional assessment - short form is a simple, non - invasive and validated scale for the detection of malnutrition in the elderly patient.

Dual-energy x-ray absorptiometry (DEXA)

Intervention Type DIAGNOSTIC_TEST

Dual-energy x-ray absorptiometry (DEXA) is the imaging technique recommended for the diagnosis of sarcopenia.

Dynamometer (Hand grip )

Intervention Type DEVICE

By placing a dynamometer in the patient's hand and asking him to apply maximum pressure to it, the muscular strength of the extremities of the limbs is estimated.

Walking speed

Intervention Type DIAGNOSTIC_TEST

Walking speed evaluates the muscular performance. The seated patient must get up and walk a distance of 6 meters as quickly as possible without the help of a third party.

Interventions

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Tongue strength measurement

The Iowa Oral Performance Instrument is a validated device for assessing the strength of the tongue. This involves placing the tip of a tube in the mouth and asking the patient to exert pressure on it.

Intervention Type DEVICE

Blood sampling

Blood sampling

Intervention Type PROCEDURE

Mini Mental State Examination (MMSE)

Also called Folstein test, it is an assessment of the patient cognitive and memory functions. It detects cognitive disorders or dementia. The MMSE is quickly realizable and explores several cognitive functions through 30 questions divided into 7 items.

Intervention Type DIAGNOSTIC_TEST

Minimal nutritional assessment (MNA-SF)

The minimal nutritional assessment - short form is a simple, non - invasive and validated scale for the detection of malnutrition in the elderly patient.

Intervention Type DIAGNOSTIC_TEST

Dual-energy x-ray absorptiometry (DEXA)

Dual-energy x-ray absorptiometry (DEXA) is the imaging technique recommended for the diagnosis of sarcopenia.

Intervention Type DIAGNOSTIC_TEST

Dynamometer (Hand grip )

By placing a dynamometer in the patient's hand and asking him to apply maximum pressure to it, the muscular strength of the extremities of the limbs is estimated.

Intervention Type DEVICE

Walking speed

Walking speed evaluates the muscular performance. The seated patient must get up and walk a distance of 6 meters as quickly as possible without the help of a third party.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

Patients hospitalized in an acute geriatric unit within the CHU Brugmann.

Exclusion Criteria

None
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Murielle Surquin

OTHER

Sponsor Role lead

Responsible Party

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Murielle Surquin

Head of clinic

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Alexandrine de Buck van Overstraeten, MD

Role: PRINCIPAL_INVESTIGATOR

CHU Brugmann

Locations

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CHU Brugmann

Brussels, , Belgium

Site Status

Countries

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Belgium

Other Identifiers

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CHUB-sarcopenia-tongue

Identifier Type: -

Identifier Source: org_study_id

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