Fatigue and Sleep in Patients With COVID-19

NCT ID: NCT04657419

Last Updated: 2021-06-16

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 60 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2021-03-08
• Study Completion Date: 2021-06-13

Brief Summary

Recent studies show that patients who have contracted COVID-19 retain very significant fatigue after resolving the infectious episode. This fatigue may be explained by low-grade inflammation. There is more data for patients with COVID-19 who have been hospitalized than for non-hospitalized patients with milder forms.

However, COVID-19 related fatigue would not only affect elderly people with severe cardiopulmonary consequences but also young subjects without severities. This notion is not very widespread and to date, COVID contracted by young subjects is considered to have very few consequences on their health.

It is also known that the prevalence of sleep debt is significant in the general population and particularly in young people, and it is also known that sleep deprivation increases low-grade inflammation and facilitates the risk of viral contamination. The association between sleep deprivation, drowsiness and possibly low-grade inflammation raise questions about the mechanisms of fatigue in the general population.

Investigators are also entitled to wonder to what extent the chronic sleep debt suffered by the French population can explain an increased risk of contamination by COVID 19 but also significant residual fatigue after COVID infection.

Bordeaux University Hospital screens 2,000 subjects per day at risk of being infected by COVID, it would be very interesting to measure, in a population of young adults aged 18-45 years, frequently exposed to a sleep debt, sleep hygiene (bedtime and wake-up times, sleep and wake-up schedules, and overall sleep satisfaction), average sleep duration, level of fatigue and drowsiness and to compare these thresholds between subjects with or without COVID 19 according to nasopharyngeal PCR.

Conditions

Covid19

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Participant

Patient or health professional coming to the Bordeaux University Hospital screening center for COVID-19 screening

survey

Intervention Type: OTHER

Self-questionnaires will be completed by the participants :

• General health and mental health
• Fatigue
• Burn-Out
• Sleepiness
• Sleep hygiene
• Symptoms of COVID

Interventions

survey

Self-questionnaires will be completed by the participants :

• General health and mental health
• Fatigue
• Burn-Out
• Sleepiness
• Sleep hygiene
• Symptoms of COVID

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Patient or healthcare professional going to screening center to perform a PCR test for COVID-19
• Between 18 and 45 years old
• Symptomatic or not
• Whether or not COVID-19 contact-case
• Accepting to participate to the research
• Informed and having expressly transmitted their non-opposition to participate in the study

Exclusion Criteria

• Participants who do not speak French or who cannot read or write
• Patients who do not have contact information for recall
• Refusal to participate in the study.
• Majors under guardianship or curatorship.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 45 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University Hospital, Bordeaux

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

CHU de Bordeaux

Bordeaux, , France

Countries

France

Other Identifiers

CHUBX 2020/52

Identifier Type: -

Identifier Source: org_study_id