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Pronation in COVID-19 Patients Undergoing Non Invasive Respiratory Support

NCT ID: NCT04649658

Last Updated: 2020-12-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

93 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-03-01

Study Completion Date

2020-11-30

Brief Summary

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Pronation seems feasible and effective in improving blood oxygenation in patients with COVID-19 pneumonia. Data are lacking on the effects of pronation on clinical outcome in this subset of patients.

Detailed Description

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Conditions

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Covid19

Keywords

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Spontaneous breathing Awake pronation COVID-19 Respiratory failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Prone position

Severe and critical COVID-19 patients undergoing non invasive respiratory support subjected to prone position

Prone position

Intervention Type BEHAVIORAL

Prone position maintained at least 3 hours/day

Standard care

Severe and critical COVID-19 patients undergoing non invasive respiratory support subjected to standard care

No interventions assigned to this group

Interventions

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Prone position

Prone position maintained at least 3 hours/day

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* patients aged ≥18 and \< 80 years old
* acute respiratory failure

Exclusion Criteria

* endotracheal intubation performed within the first 24 hours from admission,
* ceiling of escalation of intensive care
* do not intubate order as expressed by patient willing or upon clinical judgement
* missing core data at medical record analysis (clinical features at baseline, pronation information, type and time of ventilatory support required, mortality, need for tracheostomy, length of respiratory intensive care unit and hospital stay).
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Modena and Reggio Emilia

OTHER

Sponsor Role lead

Responsible Party

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Roberto Tonelli

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Azienda Ospedaliero Universitaria Policlinico di Modena

Modena, , Italy

Site Status

Countries

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Italy

Other Identifiers

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UModenaReggio10

Identifier Type: -

Identifier Source: org_study_id