Prone Positioning vs. Prone Positioning and NO Inhalation in COVID-19 ARDS.

NCT ID: NCT05715788

Last Updated: 2023-02-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-12-21

Study Completion Date

2023-12-31

Brief Summary

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The investigators aim to investigate the effects of prone positioning and prone positioning with NO inhalation for COVID-19 patients with ARDS.

Detailed Description

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The investigators aim to investigate the effects of prone positioning and prone positioning with NO inhalation for COVID-19 patients with ARDS. Patients with COVID-19-associated ARDS were ventilated in prone position with or without NO inhalation, the arterial blood gas (ABG) tests were performed at 16 hours after prone positioning.

Conditions

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Respiratory Distress Syndrome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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patients ventilated in prone position

Patients ventilated in prone position

prone positioning

Intervention Type BEHAVIORAL

vatilation in prone position

Patients ventilated in prone position with NO inhalation

Patients ventilated in prone position with NO inhalation

Nitric oxide

Intervention Type DRUG

Nitric oxide inhalation at 20 ppm

prone positioning

Intervention Type BEHAVIORAL

vatilation in prone position

Interventions

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Nitric oxide

Nitric oxide inhalation at 20 ppm

Intervention Type DRUG

prone positioning

vatilation in prone position

Intervention Type BEHAVIORAL

Other Intervention Names

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PPV

Eligibility Criteria

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Inclusion Criteria

* Adult patients with COVID-19 associated ARDS

Exclusion Criteria

* patients who have contraindication for prone positioning, including pregnant, post-abdomen surgery within a week; hypercapnic respiratory failure
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shanghai Zhongshan Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ming Zhong, PhD

Role: STUDY_CHAIR

Fudan University

Locations

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Zhongshan Hospital, Fudan University

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Ming Zhong, PhD

Role: CONTACT

‭(021) 6564 2662‬

Facility Contacts

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Ming Zhong, PhD

Role: primary

021-65642662

Other Identifiers

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ppv-vs-ppvno

Identifier Type: -

Identifier Source: org_study_id

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