Acute Effect of Passive Joint Mobilization in Non-Specific Neck Pain
NCT ID: NCT04605510
Last Updated: 2022-05-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
53 participants
INTERVENTIONAL
2021-01-01
2022-05-23
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Comparison Of Different Physiotherapy Methods In People With Non-Specific Neck Pain
NCT07004491
Mobilization With Movement Technique on the Stiffness of Cervical Muscles in Individuals With Mechanical Neck Pain
NCT06396104
The Effects of Mulligan Mobilization Technique in Older Adults With Neck Pain
NCT03507907
The Acute Effect of Proprioceptive Neuromuscular Facilitation on Cervical Range of Motion, Strength and Proprioception.
NCT04045106
Effects of Autogenic and Reciprocal Inhibition Techniques With Conventional Therapy in Mechanical Neck Pain
NCT05044078
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
The hypotheses we will test for this purpose;
H1- Passive joint mobilization application increases the range of motion of the cervical joint in women with non-specific neck pain.
H2- Passive joint mobilization application increases the pressure pain threshold in women with non-specific neck pain.
H3- Passive joint mobilization increases serum Orexin A and Neurotensin levels in women with non-specific neck pain.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
NON_RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Intervention Group
24 female participants with non-specific neck pain included in the mobilization group will undergo detailed manual cervical examination. In the evaluation, the most painful segment with dysfunction will be selected and mobilization application and algometric measurements will be performed on this segment. Grade 3 Central Posterior-Anterior (CPA) passive joint mobilization with Maitland method will be applied in 3 sets, 30 seconds, to the segment with the detected dysfunction.
Passive Cervical Joint Mobilization
It will be applied to the cervical spine, whose dysfunction is detected as a result of the evaluation. The participant will be in the prone position and Grade 3 Central Posterior-Anterior (CPA) passive joint mobilization with Maitland method will be applied for 3 sets, 30 seconds, to the segment to be treated.
Healthy Control Group
Healthy volunteer participants included in the control group will only be applied an evaluation protocol and blood samples will be taken without any application.
No interventions assigned to this group
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Passive Cervical Joint Mobilization
It will be applied to the cervical spine, whose dysfunction is detected as a result of the evaluation. The participant will be in the prone position and Grade 3 Central Posterior-Anterior (CPA) passive joint mobilization with Maitland method will be applied for 3 sets, 30 seconds, to the segment to be treated.
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Having neck pain lasting more than 30 days and being diagnosed with non-specific neck pain
* Having obtained 14/50 points and above in Neck Disability Index
* Expressing neck pain at least 34/100 points and above on a Visual Analog Scale
* Being 20-45 years old and female
For Healthy Control Group;
\- Healthy volunteers without a chronic illness and musculoskeletal pain
Exclusion Criteria
* Previously diagnosed orthopedic diseases related to the spine
* Pregnancy and having just given birth
* Within the last 3 months; use of corticosteroids, cytotoxic drugs, or immunosuppressants
* Liver or kidney failure
* Acute or chronic infections (including HIV)
* Serious pathologies (such as cancer, spondylolisthesis, rheumatoid arthritis or ankylosing spondylitis)
* Symptoms of cervical spinal stenosis (such as incoordination of hands, arms and legs, bowel and bladder incontinence)
* Radix compression (such as sensory changes, muscle weakness or decreased reflexes)
* Whiplash or a history of cervical surgery
24 Years
45 Years
FEMALE
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Pamukkale University
OTHER
Mücahit ÖZTOP
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Mücahit ÖZTOP
Research Assistant
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Nesrin YAĞCI, Professor
Role: STUDY_DIRECTOR
Pamukkale University School of Physical Therapy and Rehabilitation
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Pamukkale University School of Physical Therapy and Rehabilitation
Denizli, , Turkey (Türkiye)
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Plaza-Manzano G, Molina-Ortega F, Lomas-Vega R, Martinez-Amat A, Achalandabaso A, Hita-Contreras F. Changes in biochemical markers of pain perception and stress response after spinal manipulation. J Orthop Sports Phys Ther. 2014 Apr;44(4):231-9. doi: 10.2519/jospt.2014.4996. Epub 2014 Jan 22.
Molina-Ortega F, Lomas-Vega R, Hita-Contreras F, Plaza Manzano G, Achalandabaso A, Ramos-Morcillo AJ, Martinez-Amat A. Immediate effects of spinal manipulation on nitric oxide, substance P and pain perception. Man Ther. 2014 Oct;19(5):411-7. doi: 10.1016/j.math.2014.02.007. Epub 2014 Mar 5.
Lohman EB, Pacheco GR, Gharibvand L, Daher N, Devore K, Bains G, AlAmeri M, Berk LS. The immediate effects of cervical spine manipulation on pain and biochemical markers in females with acute non-specific mechanical neck pain: a randomized clinical trial. J Man Manip Ther. 2019 Sep;27(4):186-196. doi: 10.1080/10669817.2018.1553696. Epub 2018 Dec 11.
Maitland GD. Maitland's Vertebral Manipulation. Seventh Ed. (Hengeveld E, Banks K, eds.). Edinburgh; New York: Churchill Livingstone; 2013. https://www.elsevier.com/books/maitlands-vertebral-manipulation/hengeveld/978-0-7020-4066-5.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
60116787-020/46072
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.