Ultrasonography Guided Brain Lesions Resection:

NCT ID: NCT04569526

Last Updated: 2020-09-30

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 1 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2020-09-25
• Study Completion Date: 2021-12-30

Brief Summary

1. Evaluate the clinical value of intraoperative ultrasonography as a real-time guidance

2. Combination of data of MRI Tractography and intra operative ultrasonography will be useful in good localization of lesions or not .

3. Maximal safe resection .

Detailed Description

Accurate pre and intraoperative localization of Brain lesions is a challenge in neurosurgery specially deep intra cerebral lesions. Stereotaxy and neuronavigator played a major role in preoperative and intraoperative evaluation of exact location of intra cerebral lesions, the main drawbacks of using steriotaxy and neuronavigator that they are time consuming, complicated and expensive.(1) Nowadays we use MRI Tractography as preoperative imaging to localize lesions and there relation to neural tracts specially in eloquent brain areas, and also intraoperative ultrasonography Which act as a real-time, unexpansive and relatively simple tool for intraoperative visualization of the lesion's location, size, extent and its relationship with the surrounding tissue, also it can reveal the lesion's blood supply, it can measure the rate and direction of arterial blood flow.(2,3,4) Intraoperative ultrasonic imaging was first applied as a real-time navigation system in neurosurgery in 1980. (5) In this research we will combine the use of preoperative MRI tractography with intra operative ultrasonography in accurate localization of brain lesions and its relation with important tracts and if this combination will be beneficial and add to the safety of excision of lesions or not.

Conditions

Patients Who Are Diagnosed to Have Intracranial Lesions

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Interventions

use of intraoperative ultrasound

Ultrasonography guided brain lesions resection intra operatively for good localization

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• Patients who are diagnosed to have Intracranial lesions Patients with recurrent lesions

Exclusion Criteria

• Patients who are unfit for surgery Patients who have multifocal lesions

• Minimum Eligible Age: 1 Month
• Maximum Eligible Age: 70 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Sarah Ahmed Saad

resident doctor, neurosurgery department

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Radwan nouby mahmoud, prof

Role: STUDY_DIRECTOR

assuit nuiversity hospital neurosurgery department

wael mohamed ali, prof

Role: STUDY_DIRECTOR

assuit nuiversity hospital neurosurgery department

mohamed aly ragaee, prof

Role: STUDY_DIRECTOR

assuit nuiversity hospital neurosurgery department

Central Contacts

sarah ahmed saad tawfik, Rdr

Role: CONTACT

sarahahmedsaad@gmail.com

01099842575 ext. 002

Related Links

https://ejnpn.springeropen.com/articles/10.1186/s41983-019-0117-4

related info

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139346/

related info

Other Identifiers

intra operative ultrasound

Identifier Type: -

Identifier Source: org_study_id