Intraoperative MRI and 5-ALA Guidance to Improve the Extent of Resection in Brain Tumor Surgery
NCT ID: NCT01798771
Last Updated: 2013-02-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
108 participants
INTERVENTIONAL
2013-03-31
2016-02-29
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Control arm
5-ALA fluorescence guided surgery in patients with contrast enhancing tumors.
Control arm
5-ALA fluorescence guided surgery in patients with contrast enhancing tumors.
Interventional arm
5-ALA fluorescence guided surgery with the additional use of an intraoperative MRI for resection control in patients with contrast enhancing tumors.
Interventional arm
5-ALA fluorescence guided surgery with the additional use of an intraoperative MRI for resection control in patients with contrast enhancing tumors.
Interventions
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Interventional arm
5-ALA fluorescence guided surgery with the additional use of an intraoperative MRI for resection control in patients with contrast enhancing tumors.
Control arm
5-ALA fluorescence guided surgery in patients with contrast enhancing tumors.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* primary supratentorial intra-axial brain tumor exhibiting contrast enhancement suspected to be malignant glioma
* tumor must be deemed completely resectable by neurosurgeon
* diagnostic MRI
Exclusion Criteria
* infratentorial tumor location
* tumor location in or near eloquent areas
* multifocal tumor
* existance of contraindications to undergo MRI examination
* previous surgical treatment for an intraaxial brain tumor
18 Years
ALL
No
Sponsors
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Johann Wolfgang Goethe University Hospital
OTHER
Responsible Party
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Dr. Christian Senft
PD Dr. med. Christian Senft
Principal Investigators
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Christian Senft, MD PhD
Role: PRINCIPAL_INVESTIGATOR
Dept. of Neurosurgery, Johann Wolfgang Goethe University Hospital
Locations
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Klinik für Neurochirurgie Johann Wolfgang Goethe University
Frankfurt am Main, Hesse, Germany
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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206/12
Identifier Type: OTHER
Identifier Source: secondary_id
JohannWGUH_IMAGER
Identifier Type: -
Identifier Source: org_study_id
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