Role of Surgery in Treatment of Recurrent Brian Glioma:Prognostic Factors and Outcome

NCT ID: NCT04562077

Last Updated: 2020-09-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

25 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-10-31

Study Completion Date

2021-11-30

Brief Summary

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role of surgery in treatment of recurrent brain glioma prognostic factors and outcome measures Role of surgery : In patients with Grade I gliomas, such as pilocytic astrocytomas, resection is potentially curative.

For more diffuse invasive gliomas (Grade II or higher), initial management typically includes maximal safe resection when possible.

Increasing evidence supports an association between extent of resection and prolonged progression-free and overall survival for patients with diffuse gliomas of all types and grades Many studies reported that more that 90%of patients with glioma showed recurrence at the orginal tumor location.

Review the outcomes of re-operation in treatment of recurrent brain gliomas To determine the prognostic factors which can predict which patient would benefit from multiple surgery .

Trail to Improve the outcome of these patients and decrease rate of complications

Detailed Description

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Conditions

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Recurrent Glioma Glioma, Malignant

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

\- Patient previously operated and documented as a glioma with clinical and neuroimaging and pathological evidences.

Patients who will undergo re-operation for treatment of a recurrent brain glioma at the time of study(one year) Histological types : Different histological types of glioma.

Exclusion Criteria

* patients has brain glioma that is de novo patients who are unfit for any neurosurgical interventions. Multicentric recurrent glioma.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Mohamad Sayed Mohamad

assistant lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ahmed AlGhriany, phD

Role: STUDY_DIRECTOR

professor of neurosurgery assiut university

Ahmed AlShanawany, phD

Role: STUDY_DIRECTOR

assistant professor of neurosurgery assiut university

Mohamad S Waer

Role: PRINCIPAL_INVESTIGATOR

Resident at department of neurosurgery

Locations

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Assuit University Hospitals

Asyut, , Egypt

Site Status

Countries

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Egypt

Central Contacts

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Mohamad S Waer

Role: CONTACT

00201066479705

Facility Contacts

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Mohamad S Waer

Role: primary

00201066479705

Other Identifiers

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surgery in glioma

Identifier Type: -

Identifier Source: org_study_id

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