Effect of Vitamin D on Morbidity and Mortality of the COVID-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-04-04

Study Completion Date

2020-12-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Patients diagnosed of COVID-19 disease are randomized to receive a single dose of 100.000 IU of Cholecalciferol (Vitamin D arm) or no vitamin D (on top of the current medication used to treat COVID 19).

Clinical, radiological and biochemical outcomes of COVID 19 disease as well as mortality are evaluated.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Investigating the Role of Vitamin D in the Morbidity of COVID-19 Patients

NCT04386044

COVID-19 Vitamin D Deficiency

COMPLETED

Efficacy of Vitamin D Supplementation to Prevent the Risk of Acquiring COVID-19 in Healthcare Workers

NCT04535791

Covid19 Vitamin D

COMPLETED PHASE3

Efficacy of Vitamin D Treatment in Mortality Reduction Due to COVID-19.

NCT04621058

SAR SARS Pneumonia

COMPLETED PHASE3

Vitamin D on Prevention and Treatment of COVID-19

NCT04334005

Patients Infected With COVID-19

UNKNOWN NA

COVID-19 Morbidity in Healthcare Workers and Vitamin D Supplementation

NCT05037253

COVID-19 Respiratory Infection

COMPLETED PHASE4

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Efficacy parameters to compare both groups (vitamin D and No vitamin D).

Time to reach undetectable levels of SARS COV2 Infection.

Time of normalization of symptoms and clinical parameters.

Time of normalization of radiological images.

Time of normalization of biochemical markers.

Time of normalization of molecular inflammatory markers.

Transfer to the Intensive care Unit.

Mortality rate.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

COVID-19

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Patients receiving any form. of vitamin D excluded from the study. Randomized study (Initial serum calcidiol levels blinded )

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Active

Receiving 1 dose of 100.000 iu of Cholecalciferol when the COVID 19 Disease is diagnosed

Group Type ACTIVE_COMPARATOR

Cholecalciferol

Intervention Type DRUG

Single doe of 100.000 IU

Control

No vitamin D

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Cholecalciferol

Single doe of 100.000 IU

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Vitamin D

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* \> 18 year
* Diagnosis of COVID-19
* Accept to participate in the study ( consent)

Exclusion Criteria

* Pregnancy
* Allergy to vitamin D
* Consumption of any form of vitamin D during the last 3 months
* Expected fatal outcome in the next 24 hours
* Cognitive deterioration

Eligible Sex

ALL

Accepts Healthy Volunteers

No